Asian-Australasian Journal of Animal Sciences

Asian Australasian Association of Animal Production Societies (아세아태평양축산학회)
권호 표지
DOI QR코드

DOI QR Code

Effect of Post Insemination Progesterone Supplement on Pregnancy Rates of Repeat Breeder Friesian Cows

  • Ababneh, Mohammed M. (Department of Veterinary Clinical Sciences, Faculty of Veterinary Medicine, Jordan University of Science and Technology) ;
  • Alnimer, Mufeed A. (Department of Animal Production, Faculty of Agriculture, University of Jordan) ;
  • Husein, Mustafa Q. (Department of Animal Production, Faculty of Agriculture, Jordan University of Science and Technology)
  • Received : 2006.08.08
  • Accepted : 2007.02.26
  • Published : 2007.11.01
Download PDF
⟨ Previous Next ⟩

Abstract

Fifty repeat breeder (RB) Friesian cows were allocated to five groups of 10 cows each, to determine the effect of progesterone (P4) supplement on P4 concentrations and pregnancy rates during the periods of corpus luteum (CL) formation and development between days 2-7 and 7-12 following a spontaneous or $PGF_{2{\alpha}}$-induced estrus. Cows were artificially inseminated during $PGF_{2{\alpha}}$-induced (PGF-P4-d2 and PGF-P4-d7 groups) or spontaneous (S-P4-d2, S-P4-d7, and control groups) estrus. Progesterone-releasing intravaginal device (PRID) devoid of estrogen capsule were inserted either on d 2 (PGF-P4-d2 and S-P4-d2 groups) or d 7 (PGF-P4-d7 and S-P4-d7 groups) post-insemination and left in place for 5 days. Control cows did not receive any treatment. Blood samples were collected for progesterone analysis from all cows once daily for 4 days starting on the day of estrus (d 0) and once every 3 days thereafter until d 22. Progesterone treatment by day interaction accounted for higher plasma P4 in treated than non-treated control cows. Progesterone concentrations differed significantly (p<0.05) during metestrus (d 2 to d 7) but not during diestrus (d 7 to d 12). $PGF_{2{\alpha}}$ treatment, lactation number, service number or their interactions did not affect progesterone concentrations and pregnancy rates. Therefore, cows were grouped according to the day of P4 supplement irrespective of the $PGF_{2{\alpha}}$ treatment. Progesterone supplement on d 7 but not d 2 significantly increased (p<0.03) pregnancy rates in repeat breeding cows with four or more previous services but not in cows in their third service. In conclusion, post-insemination P4 supplement to repeat breeding cows with four or more previous services improved pregnancy rates and should be advocated when no specific reason for infertility is diagnosed. Further studies with larger numbers of repeat breeding cows under field conditions are needed to ascertain the findings of this study.

Keywords

References

  1. Ahmad, N., S. W. Beam, W. R. Butler, D. R. Deaver, R. T. Duby, E. Elder, J. E. Fortune, L. C. Griel, L. S. Jones, R. A. Milvae, L. Pate, I. Revah, D. T. Scheriber, D. H. Townson, P. C. W. Tasnag and E. K. Inskeep. 1996. Relationships of fertility to patterns of ovarian follicular development and associated hormonal profiles in dairy cows and heifers. J. Anim. Sci. 74:1943-1952. https://doi.org/10.2527/1996.7481943x
  2. Alnimer, M. A. 2005. Comparison of an oestrus synchronization protocol with Oestradiol Benzoate and $PGF2{\alpha}$ and insemination at detected oestrus to a timed insemination protocol (Ovsynch) on reproductive performance of lactating dairy cows. Reprod. Nutr. Dev. 45:699-708. https://doi.org/10.1051/rnd:2005054
  3. Alnimer, M. A. and W. Lubbadeh. 2003. Effect of Using Progesterone Releasing Intravaginal Device with Ovsynch Program on Reproduction in Dairy Cattle during Summer Season. Asian-Aust. J. Anim. Sci 16:1268-1273. https://doi.org/10.5713/ajas.2003.1268
  4. Badinga, L., R. J. Collier, W. W. Thatcher and J. Wilcox. 1985. Effects of climatic and management factors on conception rate in subtropical environment. J. Dairy Sci. 68:78-85. https://doi.org/10.3168/jds.S0022-0302(85)80800-6
  5. Burke, C. R., M. Mihm, K. L. Macmillan and J. F. Roche. 1994. Some effects of prematurely elevated concentrations of progesterone on luteal and follicular characteristics during the oestrus cycle in heifers. Anim. Reprod. Sci. 35:27-39. https://doi.org/10.1016/0378-4320(94)90004-3
  6. Butler, W. R. 2000. Nutritional interactions with reproductive performance in dairy cattle. Anim. Reprod. Sci. 60-61:449-457. https://doi.org/10.1016/S0378-4320(00)00076-2
  7. Chenault, J. R., R. E. Hornish, Y. C. Anderson, L. F. Krabill, J. F. Boucher and M. J. Prough. 2003. Concentrations of progesterone in milk of cows administered an intravaginal progesterone insert. J. Dairy Sci. 86:2050-2060. https://doi.org/10.3168/jds.S0022-0302(03)73794-1
  8. Dekruif, A. 1978. Factors influencing the fertility of a cattle population. J. Reprod. Fertil. 54:507-518. https://doi.org/10.1530/jrf.0.0540507
  9. Edmonson, A. J., I. J. Lean, L. D. Weaver, T. Farver and G. Webster. 1989.Abody condition scoring chart for Holstein dairy cows. J. Dairy Sci. 72:68-78. https://doi.org/10.3168/jds.S0022-0302(89)79081-0
  10. Garrett J. E., R. D. Geisert, M. T. Zavy and G. L. Morgan. 1988. Evidence for maternal recognition of early conceptus growth and development in beef cattle. J. Reprod. Fertil. 84:437-446. https://doi.org/10.1530/jrf.0.0840437
  11. Heuwieser, W., P. A. Oltenacu, A. J. Lednor and R. H. Foote. 1997. Evaluation of different protocols for prostaglandin synchronization to improve reproductive performance in dairy herds with low estrus detection efficiency. J. Dairy Sci. 80:2766-2774. https://doi.org/10.3168/jds.S0022-0302(97)76239-8
  12. Jainudeen, M. R. and E. S. E. Hafez. 1993. Reproductive failure in females. In: E. S. E. Hafez, Reproduction in farm animals. 6th Ed., Lea and Febiger, Pheladelphia, 261-311.
  13. Kimura, M. T., T. Nakao, M. Moriyoshi and K. Kawata. 1987. Luteal phase deficiency as a possible cause of repeat breeding in dairy cows. Br. Vet. J. 143:560. https://doi.org/10.1016/0007-1935(87)90047-9
  14. Lamming, G. E., A. O. Darwash and H. L. Back. 1989. Corpus luteum function in dairy cows and embryo mortality. J. Reprod. Fertil. Suppl. 37:245-252.
  15. Lee, C. N., E. Maurice, R. L. Ax, J. A. Ennington, W. F. Aoffman and M. D. Rown. 1983. Efficacy of gonadotropin - releasing hormone administered at the time of artificial insemination of heifers and postpartum and repeat breeder dairy cows. Am. J. Vet. Res. 44:2160-2163.
  16. Lucy, M. C. 2001. Reproductive loss in high producing dairy cattle: where will it end? J. Dairy Sci. 84:1277-1293. https://doi.org/10.3168/jds.S0022-0302(01)70158-0
  17. Lynch, P. R., K. L. Macmillan and V. K. Taufa. 1999. Treating cattle with progesterone as well as a GnRH analogue affects estrous cycle length and fertility. Anim. Reprod. Sci. 56:189-200. https://doi.org/10.1016/S0378-4320(99)00044-5
  18. Macmillan, K. L. and A. J. Peterson. 1993. A new intravaginal progesterone releasing device for cattle (CIDR-B) for oestrus synchronisation, increasing pregnancy rates and the treatment of postpartum anoestrus. Anim. Reprod. Sci. 33:1-25. https://doi.org/10.1016/0378-4320(93)90104-Y
  19. Mann, G. E. and G. E. Lamming. 1995. Progesterone inhibition of the development of the luteolytic signal in cows. J. Reprod. Fertil. 104:1-5. https://doi.org/10.1530/jrf.0.1040001
  20. Mann, G. E., G. E. Lamming and M. D. Fray. 1995. Plasma oestradiol and progesterone during early pregnancy in the cow and the effect of treatment with buserelin. Anim. Reprod. Sci. 37:121-131. https://doi.org/10.1016/0378-4320(94)01325-G
  21. Mann, G. E., G. E. Lamming, R. S. Robinson and D. C. Wathes. 1998. The regulation of interferon ${\tau}$ production and uterine hormone receptors during early pregnancy. J. Reprod. Fertil. Suppl. 54:317-328.
  22. Mann, G. E., P. Merson, M. D. Fray and G. E. Lamming. 2001. Conception rate following progesterone supplementation after sejk5cond insemination in dairy cows. Vet. J. 162:161-162. https://doi.org/10.1053/tvjl.2001.0595
  23. Mortimer, R. G, P. W. Farin and R. D. Stevens. 1997. Reproductive examination of the non- pregnant cow (Ed. R. S. Youngquist). Current Therapy in Large Animal Theriogenology. Published By W.B Saunders Co., Philadelphia, USA. pp.268-275.
  24. National Research Council. 1989. Nutrient Requirements of Dairy Cattle. 5th Ed. National Academy Sci. Washington, DC.
  25. Robinson, N. A., K. E. Leslie and J. S. Walton. 1989. Effect of treatment with progesterone on pregnancy rate and plasma concentrations of progesterone in Holstein cows. J. Dairy Sci. 72:202-207. https://doi.org/10.3168/jds.S0022-0302(89)79098-6
  26. Roussel, J. D., J. F. Beatty and K. Koonce. 1988. Gonadotropin releasing hormone therapy in functional infertility of dairy cattle. Theriogenology. 30:1115-1119. https://doi.org/10.1016/0093-691X(88)90286-5
  27. Royal, M.D., G.E. Mann and A.P.F. Flint. 2000. Strategies for reversing the trend towards subfertility in dairy cattle. Vet. J. 160:53-60. https://doi.org/10.1053/tvjl.1999.0450
  28. SAS Institute Inc. 1996. SAS/STAT User's Guide: Version 7 Edition. SAS. Institute Inc. Cary NC.
  29. Shaham- Albalancy, A., Y. Folman, M. Kaim, M. Rosenberg and D. Wolfenson. 2001. Delayed effect of low progesterone concentrations on bovine uterine PGF2alpha secretion in the subsequent oestrus cycle. Reprod. 122:643-648. https://doi.org/10.1530/rep.0.1220643
  30. Stevenson, J. S. and M. O. Mee. 1991. Pregnancy rates of Holstein cows after postinsemination treatment with a progesteronereleasing intravaginal device. J. Dairy Sci. 74:3849-3856. https://doi.org/10.3168/jds.S0022-0302(91)78577-9
  31. Thatcher, W. W., F. Moreira, J. E. P. Santos, R. C. Matoyos, F. L. Lopes, S. M. Pancarci and C.A. Risco. 2001. Effects of hormonal treatments on reproductive performance and embryo production. Theriogenol. 55:75-89. https://doi.org/10.1016/S0093-691X(00)00447-7
  32. Thatcher, M. M., C. R. Staples, G. Desnoyers, D. Oldick and E. P. Shmitt. 1994. Embryo health and mortility in sheep and cattle. J. Anim. Sci. 72(suppl.3):16. https://doi.org/10.2527/1994.72suppl_316x
  33. Thuemmel, A. E., F. C. Gwazdauskas, W. D. Whittier and M. L. McGilliard. 1992. Effect of progesterone supplementation in repeat breeder cattle on conception and plasma progesterone. J. Endocrinol. Invest. 15:393-396. https://doi.org/10.1007/BF03348762
  34. Van Cleeff, K. L., M. Drost and W. W. Thatcher. 1991. Effects of post insemination progesterone supplementation on fertility and subsequent estrous responses of dairy heifers. Theriogenol. 36:795-807. https://doi.org/10.1016/0093-691X(91)90345-E
  35. Villarroel, A., A. Martino, R. H. Don Durant, F. Deleting and W. M. Sischo. 2004. Effect of post insemination supplementation with PRID on pregnancy in repeat- breeder Holstein cows. Theriogenol. 61:1513-1520. https://doi.org/10.1016/j.theriogenology.2003.09.001
  36. Wathes, D. C. 1992. Embryonic mortality and the uterine environment. J. Endocr. 134:321-325. https://doi.org/10.1677/joe.0.1340321