$Regenaform^{(R)}$$Ossix^{(R)}$ 차단막을 이용한 골유도재생술: 증례보고

GUIDED BONE REGENERATION USING $REGENAFORM^{(R)}\;AND\;OSSIX^{(R)}$ MEMBRANE: THREE CASE REPORTS

  • 김영균 (분당서울대학교병원 치과) ;
  • 윤필영 (분당서울대학교병원 치과) ;
  • 임성철 (조선대학교 의과대학 병리학교실) ;
  • 김수관 (조선대학교 치과대학 구강악안면외과학교실)
  • Kim, Young-Kyun (Department of Oral and Maxillofacial Surgery, Section of Dentistry, Seoul National University Bundang Hospital) ;
  • Yun, Pil-Young (Department of Oral and Maxillofacial Surgery, Section of Dentistry, Seoul National University Bundang Hospital) ;
  • Lim, Sung-Chul (Department of Pathology, College of Medicine, Chosun University) ;
  • Kim, Su-Gwan (Department of Oral and Maxillofacial Surgery, College of Dentistry, Chosun University)
  • 발행 : 2007.12.31

초록

This case study investigated the clinical effect of guided bone regeneration(GBR) using $Regenaform^{(R)}\;and\;Ossix^{(R)}$ membrane and the histology of the new bone that formed just under the membranes. $Regenaform^{(R)}$ transplantation and covering with $Ossix^{(R)}$ membrane were performed to repair bone defects around implants after implantation in three patients. After $3{\sim}4$ months, the membranes were removed in a second operation, and a biopsy was taken under the membrane. The biopsies showed a bone density of $23{\sim}42%$, and subsequent prosthetic treatments were successful in all cases.

키워드

참고문헌

  1. 김영균, 김수관, 이부규: 골이식과 임프란트. Vol 2-1. 다양한 골이식술의 임상적용. 나래출판사,2007
  2. 김수민, 여환호, 김수관, 임성철: 백서에서 흡수성막과 탈회동결 건조골을 이용한 두개골결손부의 골재생. 대한구강악안면외과학회지 2002;28:290-301
  3. Reddi AH, Cunningham NS: Bone induction by osteogenin and bone morphogenetic proteins. Biomaterials 1990;11:33-34
  4. Han B, Tang B, Nimni ME: Quantitative and sensitive in vitro assay for osteoinductive activity of demineralized bone matrix. J Ortho Res. 2003; 648-654
  5. Schwartz Z, Mellonig JT, Carnes DL Jr, et al: Ability of commercial demineralized freeze-dried bone allograft to induce new bone formation. J Periodontol 1996;67:918-926 https://doi.org/10.1902/jop.1996.67.9.918
  6. Ziran B, Cheung S, Smith W, Westerheide K: Comparative efficacy of 2 different demineralized bone matrix allografts in treating longbone nonunions in heavy tobacco smokers. Am J Orthopedics 2005;329-332
  7. 김여갑, 윤병욱, 류동목 등: 임프란트 식립 시 이식된 탈회골기질을 함유한 이식재의 골형성에 대한 연구. 대한구강악안면외과학회지 2005;31:481-491
  8. Mardas N, Kostopoulos L, Stavropoulos A, Karring T: Osteogenesis by guided tissue regeneration and demineralized bone matrix. J Clin Periodontol 2003;30:176-183 https://doi.org/10.1034/j.1600-051X.2003.20031.x
  9. Stentz WC, Mealey BL, Gunsolley JC, Waldrop TC: Effect of guided bone regeneration around commercially pure titanium and hydroxyapatite-coated dental implants. II histologic analysis. J Periodontol 1997;68:933-949 https://doi.org/10.1902/jop.1997.68.10.933
  10. Liljensten E, Larsson C, Thomsen P, et al: Studies of the healing of bone grafts and the incorporation of titanium implants in grafted bone: an experimental animal model. J Mater Sci Mater Med 1998;9:535-541 https://doi.org/10.1023/A:1008844122924
  11. Babbush C: Histologic evaluation of human biopsies after dental augmentation with a demineralized bone matrix putty. Implant Dent 2003;12:325-332 https://doi.org/10.1097/01.ID.0000095466.18042.31
  12. 김명진, 김영균, 김수관: 치과수술에서 사용되는 다양한 이식 생체재료. 서울: 나래출판사. 2004
  13. Widmark G, Andersson B, Ivanoff CJ: Mandibular bone graft in the anterior maxilla for single-tooth implants. Presentation of a surgical method. Int J Oral Maxillofac Surg 1997;26:106-109
  14. Morone MA, Boden SD: Experimental posterolateral lumbar spinal fusion with a demineralized bone matrix gel. Spine 1998;23:159 https://doi.org/10.1097/00007632-199801150-00003
  15. Friedman A, Strietzel FP, Maretzki B, Pitaru S, Bernimoulin JP: Observation on a new collagen barrier membrane in 16 consecutively treated patients. Clinical and histological finding. J Periodontol 2001;72:1616-1623 https://doi.org/10.1902/jop.2001.72.11.1616
  16. Friedman A, Strietzel FP, Maretzki B, Pitaru S, Bernimoulin JP: Histological assessment of augmented jaw bone utilizing a new collagen barrier membrane compare to a standard barrier membrane to protect a granular bone substitute material: a randomized clinical trial. Clin Oral Implants Res 2003;13:587-594 https://doi.org/10.1034/j.1600-0501.2002.130603.x