Journal of the Korean Association of Oral and Maxillofacial Surgeons

The Korean Association of Oral and Maxillofacial Surgeons (대한구강악안면외과학회)
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HISTOMORPHOMETRIC ANALYSIS OF MAXILLARY SINUS AUGMENTATION WITH DEPROTEINIZED BOVINE BONE(BIO-$OSS^{(R)}$) AND VARIOUS ABSORBABLE MEMBRANE

탈단백 소뼈 기질과 다양한 종류의 흡수성 막을 이용한 상악동 거상술 후의 조직-형태학적 분석

  • Jang, Tae-Hwa (Dept. of Oral & Maxillofacial Surgery, School of Dentistry, Kyungpook National University) ;
  • Jang, Yoon-Je (Jang Yoon-Je Dental Clinic) ;
  • Kwon, Tae-Geon (Dept. of Oral & Maxillofacial Surgery, School of Dentistry, Kyungpook National University) ;
  • Lee, Sang-Han (Dept. of Oral & Maxillofacial Surgery, School of Dentistry, Kyungpook National University)
  • 장태화 (경북대학교 치과대학 구강악안면외과학교실) ;
  • 장윤제 (장윤제 연합치과) ;
  • 권대근 (경북대학교 치과대학 구강악안면외과학교실) ;
  • 이상한 (경북대학교 치과대학 구강악안면외과학교실)
  • Published : 2007.12.31
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Abstract

Purpose: The aim of the present study was to evaluate the effect of Bio-Oss on bone formation in terms of healing period and type of membrane so that determine the most suitable condition for implant fixation in grafted maxilla. Material & Method: Forty-five biopsy specimens from graft site were evaluated. Sinus lift was performed in the patients with reduced alveolar bone height(less than 5mm). The specimen was taken at the time of implant fixation, which was performed at least 5 months after the sinus lift procedure. All specimens were stained with H&E and Trichrome staining and evaluated histomorphometrically. Result: The results showed that Bio-Oss particle was in direct contact with newly formed bone in all cases. In the present study, the amount of newly formed bone and the residual bone substitute material were not statistically different according to various membrane and different healing period. There was no difference between the histological feature of the specimen of 5 and 31 months. No statistical significance was detected between male and female. Conclusion: The result implies that Bio-Oss does not seem to be resorbed over time regardless of the type of the membranes. The further investigation is needed to clarify this issue with the extended period of follow-up.

Keywords

References

  1. Boyne PJ, James R: Grafting of the maxillary sinus floor with autogenous marrow and bone. J Oral Surg 1980;38:613-618
  2. Groeneveld EH, van den Bergh JP, Holzmann P, ten Bruggenkate CM, Tuinzing DB, Burger EH: Mineralization processes in demineralized bone matrix grafts in human maxillary sinus floor elevation. J Biomed Mater Res 1999;48:393-402 https://doi.org/10.1002/(SICI)1097-4636(1999)48:4<393::AID-JBM1>3.0.CO;2-C
  3. Artzi Z, Nemcovsky CE: The application of deproteinized bovine bone mineral for ridge preservation prior to implantation. Clinical and histological observations in a case report. J Periodontol 1998;69:1062-1067 https://doi.org/10.1902/jop.1998.69.9.1062
  4. Wagner JR: A 3 1/2-year clinical evaluation of resorbable hydroxylapatite OsteoGen (HA Resorb) used for sinus lift augmentations in conjunction with the insertion of endosseous implants. J Oral Implantol 1991;17:152-164
  5. Smiler DG, Holmes RE: Sinus lift procedure using porous hydroxyapatite: a preliminary clinical report. J Oral Implantol 1987;13:239-253
  6. Saffar JL, Colombier ML, Detienville R: Bone formation in tricalcium phosphate-filled periodontal intrabony lesions. Histological observation in humans. J Periodontol 1990;61:209-216 https://doi.org/10.1902/jop.1990.61.4.209
  7. Furusawa T, Mizunuma K: Osteoconductive properties and efficacy of resorbable bioactive glass as a bone-grafting material. Implant Dent 1997;6:93-101 https://doi.org/10.1097/00008505-199700620-00003
  8. Tadjoedin ES, De Lange GL, Holzmann PJ, Kuiper L, Burger EH: Histological observation on biopsies harvested following sinus floor elevation using a bioactive glass material of narrow size range. Clin Oral Res 2000;11:334-344 https://doi.org/10.1034/j.1600-0501.2000.011004334.x
  9. Tadjoedin ES, De Lange GL, Lyaruu DM, Kuiper L, Burger EH: High concentration of bioactive glass material (BioGran) versus autogeous bone for sinus floor elevation: Histomorphometrical observations on three split mouth clinical cases. Clin Oral Res 2002;13:428-436 https://doi.org/10.1034/j.1600-0501.2002.130412.x
  10. Tadjoedin ES, De Lange GL, Bronckers ALJJ, Lyaruu DM, Burger EH: Deproteinized cancellous bovine bone (Bio-Oss) as bone substitute for sinus floor elevation. A retrospective, histomorphomeritical study of five cases. J Clin Periodontol 2003;30:261-270 https://doi.org/10.1034/j.1600-051X.2003.01099.x
  11. Yildirim M, Spiekermann H, Biesterfeld S, Edelhoff D: Maxillary sinus augmentation using xenogenic bone substitute material Bio-Oss in combination with venous blood. Clin Oral Impl Res 2000;11:217-229 https://doi.org/10.1034/j.1600-0501.2000.011003217.x
  12. Froum SJ, Tarnow DP, Wallace SS, Rohrer MD, Cho SC: sinus floor elevation using anorganic bovine bone matrix (OsteoGraf/N) with and without autogenous bone: A clinical, histologic, radiographic and histomorphometric analysis-Part 2 of an ongoing study. Int J Periodontics Restorative Dent 1998;18:529-543
  13. Rothamel D, Schwarz F, Sager M, Herten M, Sculean A, Becker J: Biodegradation of differently cross-linked collagen membrane: an experimental study in the rat. Clin Oral Implants Res 2005;16:369-378 https://doi.org/10.1111/j.1600-0501.2005.01108.x
  14. Zitzmann NU, Naef R, Scharer P: Resorbable versus nonresorbable membranes in combination with Bio-Oss for guided bone regeneration. Int J Oral Max Impl 1997;12:844-852
  15. Pitaru S, Tal H, Soldinger M, Grosskopf A, Noff M: Partial regeneration of periodontal tissues using collagen barrier. Initial observations in the canine. J Periodontol 1988;59:380-386 https://doi.org/10.1902/jop.1988.59.6.380
  16. Hutmacher D, Hurzeler MB, Schliephake H: A review of material properties of biodegradable and bioresorbable polymers and devices for GTR and GBR applications. Int J Oral Max Impl 1996;11:667-678
  17. Locci P, Calvitti M, Belcastro S, Pugliese M, Guerra M, Marinucci L, Staffolani N, Becchetti E: Phenotype expression of gingival fibroblasts cultured on membranes used in guided tissue regeneration. J Periodontol 1997;68:857-863 https://doi.org/10.1902/jop.1997.68.9.857
  18. Postlethwaite AE, Seyer JM, Kang AH: Chemotactic attraction of human fibroblasts to type I, II, and III collagens and collagen-derived peptides. Proc Nati Acad Sci USA 1978;75:871-875
  19. Yaffe A, Ehrlich J, Shoshan S: Restoration of periodontal attachment employing enriched collagen solution in the dog. J Periodontol 1984;55:623-628 https://doi.org/10.1902/jop.1984.55.11.623
  20. Mattson JS, Gallagher SJ, Jabro MH: The use of 2 bioabsorbable barrier membranes in the treatment of interproximal intrabony periodontal defects. J Periodontol 1999;70:510-517 https://doi.org/10.1902/jop.1999.70.5.510
  21. Yukna CN, Yukna RA: Multi-center evaluation of bioabsorbable collagen membrane for guided tissue regeneration in human Class II furcations. J Periodontol 1996;67:650-657 https://doi.org/10.1902/jop.1996.67.7.650
  22. Maurizio P, Gian AF: Bone reactions to anorganic bovine bone(Bio-Oss) used in sinus augmentation procedures: A histologic long-term report of 20 cases in humans. Int J Oral Maxillofac Implants 1999;14:835-840
  23. 김진욱, 박인숙, 이상한, 김진수, 장현중, 권대근, 김현수: 가토의 두개골 결선부에 이식한 human DBM (Grafton$^{\circleR}$)의 효과. 대한악안면성형재건외과학회지 2006;28:118-26
  24. Jensen SS, Aaboe M, Pinholt EM, Hjorting-Hansen E, Melsen F, Ruyter IE: Tissue reaction and material characteristics of four bone substitutes. Int J Oral Maxillofac Implants 1996;11:55-66
  25. Clergeau LP, Danan M, Clergeau-Guerithault S, Brion M: Healing response to anorganic bone implantation in periodontal bony defects in dogs. Part I. Bone regeneration. A micrographic study. J Periodontol 1996;67:1140-1149
  26. Andreas KS, Karl D: BIO-OSS - A Resorbable Bone Substitute? J Long Term Eff Med Implants. 1998;8:201-209
  27. Skoglund A, Hising P, Young C: A clinical and histologic examination in humans of the osseous response to implanted natural bone mineral. Int J Oral Maxillofac Implants 1997;12:194-199
  28. Berglundh T, Lindhe J: Healing around implants placed in bone defects treated with Bio-Oss. An experimental study in the dog. Clinic Oral Res 1997;8:117-124 https://doi.org/10.1034/j.1600-0501.1997.080206.x
  29. Zitzmann NU, Scharer P, Marinello CP, Schupbach P, Berglundh T: Alveolar ridge augmentation with Bio-Oss: a histologic study in humans. Int J Periodontics Restorative Dent. 2001;21:220-231
  30. Wallace SS, Froum SJ, Cho SC, Elian N, Monteiro D, Kim BS, Tarnow DP: Sinus augmentation utilizing anorganic bovine bone (Bio-Oss) with absorbable and nonabsorbable membranes placed over the lateral window: histomorphometric and clinical analysis. Int J Periodontics Restorative Dent 2005;25:551-559
  31. Small SA, Zinner ID, Panno FV, Shapiro HJ, Stein JI: Augmenting the maxillary sinus for implants: Report of 27 patients. Int J Oral Maxillofac Implants 1993;8:523-528
  32. Hulzeler MB, Kirsch A, Ackermann KL, Quinones CR: Reconstruction of the severely resorbed maxilla with dental implants in the augmented maxillary sinus: A 5-year clinical investigation. Int J Oral Maxillofac Implants 1996;11:466-475
  33. Peleg M, Mazor Z, Ghaushu G, Garg AK: Sinus floor augmentation with simultaneous implant placement in the severely atrophic maxilla. J Periodontol 1998;69:1397-1403 https://doi.org/10.1902/jop.1998.69.12.1397
  34. Peleg M, Mazor Z, Garg AK: Augmentation grafting of the maxillary sinus and simultaneous implant placement in patients with 3 to 5mm of residual bone height. Int J Oral Maxillofac Implants 1999;14:549-556
  35. Lorenzoni M, Pertl C, Wegscheider W: Retrospective analysis of Frialit-2 implants in the augmented sinus. Int J Periodontics Restorative Dent 2000;20:255-267
  36. Avera SP, Stampley WA, McAllister BS: Histologic and clinical observation of resorbable and nonresorbable barrier membranes used in maxillary sinus graft containment. Int J Maxillofac Implants 1997;12:88-94
  37. 김수관, 강태호, 박정열: 임플란트 식립을 위한 상악동 점막거상술: 문헌고찰. 대한구강악안면외과학회지 2000;26:527-532
  38. 홍순민: 탈단백 우골 (Deproteinized Bovine Bone Mineral)을 이용한 상악동 골이식술: 측면 접근법의 문헌 고찰. 대한구강악안면외과학회지 2006;32:482-487