대한화장품학회지 (Journal of the Society of Cosmetic Scientists of Korea)

  • 제33권3호
  • /
  • Pages.175-179
  • /
  • 2007
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  • 1226-2587(pISSN)
  • /
  • 2288-9507(eISSN)
대한화장품학회 (Society of Cosmetic Scientists of Korea)
권호 표지

제주 자생 식물들에 대한 항비만 효능에 대한 연구

The Study on Anti-obesity Activity of the Wild Plants of Jeju Island

  • 박덕훈 (바이오스펙트럼(주) 생명과학연구소) ;
  • 정은선 (바이오스펙트럼(주) 생명과학연구소) ;
  • 이종성 (바이오스펙트럼(주) 생명과학연구소) ;
  • 정광선 (스킨큐어코스메틱(주)) ;
  • 김새봄 (바이오스펙트럼(주) 생명과학연구소) ;
  • 허성란 (바이오스펙트럼(주) 생명과학연구소)
  • 발행 : 2007.09.30
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초록

본 연구에서는 제주도에서 자생하는 30여 종의 식물추출물에 대한 항비만 효능을 조사하였다. 항비만 효능은 in vitro oil red-O staining 방법을 이용하여 지방전구세포 3T3-L1에서 분화억제력을 측정하였다. 그 결과, 30여 종의 식물 중에서 약도라지, 호장근, 유근피 등을 포함한 6종의 식물이 지방전구세포 3T3-L1의 분화를 억제하였다. 지방전구세포의 분화를 억제하는 물질 중 유근피, 약쑥, 호장근, 후박 4종은 우수한 항산화 효능도 동시에 가지고 있음을 확인하였다. 이러한 결과를 통해, 본 실험에서 확보된 추출물이 항비만 물질로 사용될 수 있는 가능성을 확인하였다.

In this study, we investigated the anti-obesity activity of extracts collected from wild plants in Jeju island. The inhibitory effect of plant extracts on the differentiation of preadipocyte 3T3-L1 was examined by oil red-O staining. We found that extracts collected from 6 plants among 31 plants, namely, Aralia elata(Miq.) Seem, Polygonum multiflorum Thunberg, Artemisia asiatica, platycodon grandiflorum(Jacq.) A. Dc., Polygonum cuspidatum S. et Z., Magnolia obovata Thunb, significantly inhibited preadipocyte differentiation. Additionally, 4 plant extracts were also found to have antioxidant activities in DPPH radical scavenging assay. Taken together, these results show that 6 plant extracts suppress the differentiation of preadipocytes, suggesting the potential use of 6 plant extracts as anti-obesity agents.

키워드

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