한국재료학회지 (Korean Journal of Materials Research)

  • 제17권11호
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  • Pages.622-627
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  • 2007
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  • 1225-0562(pISSN)
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  • 2287-7258(eISSN)
한국재료학회 (Materials Research Society of Korea)
권호 표지
DOI QR코드

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NaOH 처리에 따른 다공성 PCL 지지체의 의사체액 환경에서의 아파타이트 형성

Apatite Formation of NaOH-treated Porous PCL Scaffolds in Simulated Body Fluid

  • 이향미 (부산대학교 재료공학부) ;
  • 진형호 (부산대학교 재료공학부) ;
  • 현용택 (한국기계연구원 재료기술연구소 미래기술연구부) ;
  • 박홍채 (부산대학교 재료공학부) ;
  • 윤석영 (부산대학교 재료공학부)
  • Lee, Hyang-Mi (School of Materials Science and Engineering, Pusan National University) ;
  • Jin, Hyeong-Ho (School of Materials Science and Engineering, Pusan National University) ;
  • Hyun, Yong-Taek (Department of Future Technology, Korea Institute of Machinery and Materials) ;
  • Park, Hong-Chae (School of Materials Science and Engineering, Pusan National University) ;
  • Yoon, Seog-Young (School of Materials Science and Engineering, Pusan National University)
  • 발행 : 2007.11.27
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초록

Porous poly(e-caprolactone) (PCL) scaffolds were fabricated by salt leaching method. The PCL scaffolds were treated with aqueous NaOH for 0h, 2h, 4h, 8h, and 12h at $40^{\circ}C$. The NaOH-treated PCL scaffolds were dipped in $CaCl_2$ and $K_2HPO_4{\cdot}_3H_2O$ solution alternately three times to induce apatite nuclei onto the surface of the scaffolds. The NaOH-treated PCL scaffolds were immersed into SBF solution for 1day to grow the apatite. The apatite formation were investigated as a fuction of NaOH treatment time. The hydrophilicty and surface area of the PCL scaffolds were increased with NaOH-treatment time. The NaOH-treated PCL scaffolds were successfully formed a dense and uniform bone-like apatite layer after immersion for 1 day in SBF solution.

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