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Synthesis and Properties of Soluble and Stable Silyl End-capped Bis-thienylanthracene Oligomers

  • Choi, Jung-Hei (Department of Chemistry and the Center for Plastic Information System, Pusan National University) ;
  • Cho, Dae-Won (Department of Chemistry and the Center for Plastic Information System, Pusan National University) ;
  • Sung, Nam-Kyoung (Department of Chemistry and the Center for Plastic Information System, Pusan National University) ;
  • Jin, Sung-Ho (Department of Chemistry Education and the Center for Plastic Information System, Pusan National University) ;
  • Yoon, Ung-Chan (Department of Chemistry and the Center for Plastic Information System, Pusan National University)
  • 발행 : 2007.11.20

초록

Analyzed are recent advances in design of novel boronared conjugates of synthetic and natural porphyrins and chlorins. These compounds showed high efficacy as cytotoxic agents for tumor cells in culture and as phototoxins in photodynamic therapy of tumor xenografts. Thus, boronated porphyrins and chlorins emerge as promising class of anticancer agents with potentially multiple advantages: the chemotherapeutic drugs alone and photo- and radiosensitizers in binary treatments.

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참고문헌

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피인용 문헌

  1. Synthesis and Characterization of Soluble Silyl End-capped Arene-Thiophene Co-Oligomers vol.36, pp.5, 2015, https://doi.org/10.1002/bkcs.10257
  2. Synthesis and Characterization of Bis-Thienyl-9,10-anthracenes Containing Electron Withdrawing 2-Cyanoacrylic Acid or 2-Methylenemalononitrile Group vol.32, pp.8, 2011, https://doi.org/10.5012/bkcs.2011.32.8.3081