Journal of The Korean Society of Clinical Toxicology (대한임상독성학회지)

Korean society of Clincal Toxicology (대한임상독성학회)
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A Case of anterograde amnesia with hippocampal lesions following glufosinate intoxication

Glufosinate ammonium 중독 후에 발생한 해마 손상에 의한 선행성 기억상실 1례

  • Seol Seung-Hwan (Department of Emergency Medicine, Ajou University School of Medicine) ;
  • Park Hyeon-Soo (Department of Emergency Medicine, Ajou University School of Medicine) ;
  • Ahn Jung-Hwan (Department of Emergency Medicine, Ajou University School of Medicine) ;
  • Park Hee-Young (Department of Neurology, Ajou University School of Medicine) ;
  • Lee Phil-Hyu (Department of Neurology, Ajou University School of Medicine) ;
  • Kim Gi-Woon (Department of Emergency Medicine, Ajou University School of Medicine)
  • 설승환 (아주대학교 의과대학 응급의학교실) ;
  • 박현수 (아주대학교 의과대학 응급의학교실) ;
  • 안정환 (아주대학교 의과대학 응급의학교실) ;
  • 박희영 (아주대학교 의과대학 신경과학교실) ;
  • 이필휴 (아주대학교 의과대학 신경과학교실) ;
  • 김기운 (아주대학교 의과대학 응급의학교실)
  • Published : 2006.06.01
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Abstract

Glufosinate ammonium (GLA), a phosphinic acid derivate of glutamate, is a broad-spectrum contact herbicide. It structurally resembles glutamate, a typical excitatory amino acid in the central nervous system. In korea, the ingestion of GLA for suicidal attempt or accidental event has increased. The neurological complication of GLA intoxication are characterized by loss of consciousness, convulsion, or memory impairment. But, the exact mechanism of GLA toxicity is yet unknown. This report is about a patient with GLA intoxication who showed anterograde amnesia with selective bilateral hip-pocampal lesions supported GLA intoxication with literature reviews supported.

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