대한의용생체공학회:의공학회지 (Journal of Biomedical Engineering Research)

  • 제27권4호
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  • Pages.154-163
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  • 2006
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  • 1229-0807(pISSN)
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  • 2288-9396(eISSN)
대한의용생체공학회 (The Korean Society of Medical and Biological Engineering)
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A Low-noise Multichannel Magnetocardiogram System for the Diagnosis of Heart Electric Activity

  • Lee, Yong-Ho (Bio-signal Research Center, Korea Research Institute of Standards and Science) ;
  • Kim, Ki-Woong (Bio-signal Research Center, Korea Research Institute of Standards and Science) ;
  • Kim, Jin-Mok (Bio-signal Research Center, Korea Research Institute of Standards and Science) ;
  • Kwon, Hyuk-Chan (Bio-signal Research Center, Korea Research Institute of Standards and Science) ;
  • Yu, Kwon-Kyu (Bio-signal Research Center, Korea Research Institute of Standards and Science) ;
  • Kim, In-Seon (Bio-signal Research Center, Korea Research Institute of Standards and Science) ;
  • Park, Yong-Ki (Bio-signal Research Center, Korea Research Institute of Standards and Science)
  • 발행 : 2006.08.01
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초록

A 64-channel magnetocardiogram (MCG) system using low-noise superconducting quantum interference device (SQUID) planar gradiometers was developed for the measurements of cardiac magnetic fields generated by the heart electric activity. Owing to high flux-to-voltage transfers of double relaxation oscillation SQUID (DROS) sensors, the flux-locked loop electronics for SQUID operation could be made simpler than that of conventional DC SQUIDs, and the SQUID control was done automatically through a fiber-optic cable. The pickup coils are first-order planar gradiometers with a baseline of 4 em. The insert has 64 planar gradiometers as the sensing channels and were arranged to measure MCG field components tangential to the chest surface. When the 64-channel insert was in operation everyday, the average boil-off rate of the dewar was 3.6 Lid. The noise spectrum of the SQUID planar gradiometer system was about 5 fT$_{rms}$/$\checkmark$Hz at 100 Hz, operated inside a moderately shielded room. The MCG measurements were done at a sampling rate of 500 Hz or 1 kHz, and realtime display of MCG traces and heart rate were displayed. After the acquisition, magnetic field mapping and current mapping could be done. From the magnetic and current information, parameters for the diagnosis of myocardial ischemia were evaluated to be compared with other diagnostic methods.

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참고문헌

  1. G. Stroink, W. Moshage, and S. Achenbach, Cardiomagnetism, In: Magnetism in Medicine, W. Andrii and H. Nowak Ed., Berlin: Wiley-VCH, pp.136-l89, 1998
  2. H. Nowak, Biomagnetism, In: Magnetism in Medicine, W. Andra and H. Nowak Ed., Berlin: Wiley-VCR, pp.85-135, 1998
  3. J. W. Park, and F. Jung, 'Qualitative and Quantitative Description of Myocardial Ischemia by means of magnetocardiography,' Biomed. Technik., vol. 49, pp.267-273, 2004
  4. R. Fenici, D. Brisinda, and A. M. Meloni, 'Clinical application of magnetocardiography,' Expert Rev. Mol. Diagn., vol. 5, pp.291-313,2005 https://doi.org/10.1586/14737159.5.3.291
  5. S. Yamada, and I. Yamaguchi, 'Magnetocardiograms in clinical medicine: unique information on cardiac ischemia, arrhythmias, and fetal diagnosis,' Internal Medicine, vol. 44, pp: 1-19,2005 https://doi.org/10.2169/internalmedicine.44.1
  6. V. Pizzella, S. D. Penna, C. Del Gratta, and G. L. Romani, 'SQUID systems for biomagnetic imaging,' Supercond. Sci. Technol., vol. 12, pp.R79-R114, 2001
  7. D. J. Adelerhof, H. Nijstad, J. Flokstra, and H. Rogalla, '(Double) relaxation oscillation SQUIDs with high flux-tovoltage transfer: Simulations and experiments,' J. Appl. Phys., vol. 76, pp.3875-3886, 1994 https://doi.org/10.1063/1.357392
  8. Y. H. Lee, H. C. Kwon, J. M. Kim, Y. K. Park, and J. C. Park, 'Double relaxation oscillation SQUID with reference junction for biomagnetic multi-channel applications,' Appl. Supercond., vol. 5, pp.413-418, 1998 https://doi.org/10.1016/S0964-1807(98)00063-5
  9. Y. H. Lee,J. M. Kim, K. Ki, H. Kwon, K. K. Yu, I. S. Kim, and Y. K. park, '64-channel magnetocardiogram system based on double relaxation oscillation SQUID planar gradiometers,' Supercond. Sci. Technol., vol. 19, pp.S284-288, 2006 https://doi.org/10.1088/0953-2048/19/5/S25
  10. J. M. Kim, Y. H. Lee, K. Kim, H. Kwon, Y. K. Park, and I. Sasada, 'Compact readout electronics for 62-channels DROS magnetocardiography system,' IEEE Trans. Appl. Supercond., vol. 15, pp.644-647, 2005 https://doi.org/10.1109/TASC.2005.849982
  11. K. Kim, Y. H. Lee, H. Kwon, J. M. Kim, I. S. Kim, and Y. K. Park, 'Optimal sensor distribution for measuring the tangential field components in MCG,' in Proc. 14th Int. Conf Biomagnetism Boston, 2004, pp.359-360
  12. J. Nurnminen, S. Ahlfors, R. Ilmoniemi, J. Montonen and J. Nenonen, 'Transformation of multichannel magnetocardiographic signals to standard grid form,' IEEE Trans. Biomed. Eng., vol. 42, pp.72-78, 1995 https://doi.org/10.1109/10.362916