Tuberculosis and Respiratory Diseases

The Korean Academy of Tuberculosis and Respiratory Diseases (대한결핵및호흡기학회)
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A Case of Multiple Endobronchial Metastases from Prostatic Carcinoma

전립선 암의 다발성 기관지내전이 1예

  • Lee, Jeong Eun (Division of Pulmonology, Department of Internal Medicine, Chungnam National University Hospital & Cancer Research Institute) ;
  • Lee, You Jin (Division of Pulmonology, Department of Internal Medicine, Chungnam National University Hospital & Cancer Research Institute) ;
  • Jeong, Mi Kyong (Division of Pulmonology, Department of Internal Medicine, Chungnam National University Hospital & Cancer Research Institute) ;
  • Park, Hee Sun (Division of Pulmonology, Department of Internal Medicine, Chungnam National University Hospital & Cancer Research Institute) ;
  • Jung, Sung Soo (Division of Pulmonology, Department of Internal Medicine, Chungnam National University Hospital & Cancer Research Institute) ;
  • Kim, Ju Ock (Division of Pulmonology, Department of Internal Medicine, Chungnam National University Hospital & Cancer Research Institute) ;
  • Kang, Dae Young (Department of Pathology, Chungnam National University Hospital & Cancer Research Institute) ;
  • Sul, Chong Koo (Department of Urology, Chungnam National University Hospital & Cancer Research Institute) ;
  • Kim, Sun Young (Division of Pulmonology, Department of Internal Medicine, Chungnam National University Hospital & Cancer Research Institute)
  • 이정은 (충남대학교 의과대학 내과학교실) ;
  • 이유진 (충남대학교 의과대학 내과학교실) ;
  • 정미경 (충남대학교 의과대학 내과학교실) ;
  • 박희선 (충남대학교 의과대학 내과학교실) ;
  • 정성수 (충남대학교 의과대학 내과학교실) ;
  • 김주옥 (충남대학교 의과대학 내과학교실) ;
  • 강대영 ;
  • 설종구 ;
  • 김선영 (충남대학교 의과대학 내과학교실)
  • Received : 2006.04.24
  • Accepted : 2006.06.30
  • Published : 2006.08.30
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Abstract

The lung is the most common site for the metastasis of extrapulmonary malignant tumors. However, endobronchial metastases (EBM) from extrapulmonary malignant tumors are rare. The most common extrathoracic malignancies associated with EBM are the breast, renal and colorectal carcinomas. Lung metastasis from prostate cancer is often encountered but EBM is rare. We report a 74-year old man with endobronchial metastases from prostatic carcinoma presented with cough. The diagnosis of prostatic cancer and the endobronchial metastasis were confirmed by immunohistological staining with the prostate specific antigen. Hormonal therapy (lutenizing hormone releasing hormone agonist) was applied to this patient.

Keywords

References

  1. Braman SS, Witcomb ME. Endobronchial metastases. Arch Intern Med 1975;135:543-7 https://doi.org/10.1001/archinte.135.4.543
  2. Baumgartner WA, Mark JB. Metastatic malignancies from distant sites to the tracheobronchial tree. J Thorac Cardiovasc Surg 1980;79:499-503
  3. Pass HI, Donigtom JS. Metastatic cancer to the lung. In: DeVita VT, Hellman S, Rosenberg SA, editors. Cancer: principles and practice of oncology. Philadelphia: Lippincot-Rowen Publishers 1997. p. 2536-50
  4. Scoggins WG, Witten JA Jr, Texter JH Jr, Hazra TA.Endobronchial metastasis from prostatic cancer in patients with renal cell carcinoma. Urology 1978;12: 207-9 https://doi.org/10.1016/0090-4295(78)90336-9
  5. Stranzl H, Gabor S, Mayer R, Prettenhofer U, Wurzinger G, Hackl A. Fractionated intraluminal HDR 192Ir brachytherapy as palliative treatment in patients with endobronchial metastases from nonbronchogenic primaries. Strahlenther Onkol 2002;178: 442-5 https://doi.org/10.1007/s00066-002-0943-6
  6. Lee DW, Ro JY, Sahin AA, Lee JS, Ayala AG. Mucinous-adenocarcinoma of the prostate with endobronchial metastasis. Am J Clin Pathol 1990;94:641-5 https://doi.org/10.1093/ajcp/94.5.641
  7. Quantrill SJ, Burt PA, Barber PV, Stout R. Treatment of endobronchial metastases with intraluminal radiotherapy. Respir Med 2000;94:369-72 https://doi.org/10.1053/rmed.1999.0731
  8. Heitmiller RF, Marasco WJ, Hruban RH, Marsh BR. Endobronchial metastasis. J Thorac Cardiovasc Surg 1993;106:537-42
  9. Katsimbri PP, Bamias AT, Froudarakis ME, Peponis IA, Constantopoulos SH, Pavlidis NA. Endobronchial metastases secondary to solid tumors: report of eight cases and review of the literature. Lung Cancer 2000;28:163-70 https://doi.org/10.1016/S0169-5002(99)00134-8
  10. Salud A, Porcel JM, Rovirosa A, Bellmunt J. Endobronchial metastatic disease: analysis of 32 cases. J Surg Oncol 1996;62:249-52 https://doi.org/10.1002/(SICI)1096-9098(199608)62:4<249::AID-JSO4>3.0.CO;2-6
  11. Poe RH, Israel RH, Qazi R, Ortiz C, Marin MG, Dale RC, et al. Sensitivity, specificity, and predictive values of bronchoscopy in neoplasm metastatic to the lung. Chest 1985;88:84-8 https://doi.org/10.1378/chest.88.1.84
  12. Diaz G, Jimenez D, Dominguez-Reboiras S, Carrillo F, Perez-Rodriguez-E. Yield of bronchoscopy in the diagnosis of neoplasm metastatic to lung. Respir Med 2003;97:27-9 https://doi.org/10.1053/rmed.2002.1422
  13. Nagji M, Tabei SZ, Castro A, Chu TM, Murphy GP, Wang MC, et al. Prostatic specific antigen: an immunohistochemical marker for prostatic neoplasm. Cancer 1981;48:1229-32 https://doi.org/10.1002/1097-0142(19810901)48:5<1229::AID-CNCR2820480529>3.0.CO;2-L
  14. Lalli C, Gogia H, Raju L. Multiple endobronchial metastases from carcinoma of prostate. Urology 1983; 21:164-5 https://doi.org/10.1016/0090-4295(83)90015-8
  15. Carlin BW, Harrel JH, Olson LK, Moser KM. Endobronchial metastases due to colorectal carcinoma. Chest 1989;96:1110-4 https://doi.org/10.1378/chest.96.5.1110