Journal of Microbiology and Biotechnology

The Korean Society for Microbiology and Biotechnology (한국미생물·생명공학회)
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Novel Function of Cytokinin: A Signaling Molecule for Promotion of Antibiotic Production in Streptomycetes

  • Yang Young-Yell (Institute of Bioscience and Biotechnology, Department of Biological Science, Myongji University) ;
  • Zhao Xin-Qing (Institute of Bioscience and Biotechnology, Department of Biological Science, Myongji University) ;
  • Jin Ying-Yu (Institute of Bioscience and Biotechnology, Department of Biological Science, Myongji University) ;
  • Huh Jung-Hyun (Institute of Bioscience and Biotechnology, Department of Biological Science, Myongji University) ;
  • Cheng Jin-Hua (Institute of Bioscience and Biotechnology, Department of Biological Science, Myongji University) ;
  • Singh Deepak (Institute of Bioscience and Biotechnology, Department of Biological Science, Myongji University) ;
  • Kwon Hyung-Jin (Institute of Bioscience and Biotechnology, Department of Biological Science, Myongji University) ;
  • Suh Joo-Won (Institute of Bioscience and Biotechnology, Department of Biological Science, Myongji University)
  • Published : 2006.06.01
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Abstract

Cytokinin has been known to act as a plant hormone to promote cell division and function in diverse processes in plant growth and development. Besides being produced in plants, it is also produced by various bacteria and fungi; however, its ecological significance is still unclear. In this report, we present an interesting finding that transzeatin riboside (tZR), a naturally occurring cytokinin compound, increased antibiotic production in many different streptomycetes, including Streptomyces coelicolor Ml3O, S. pristinaespiralis ATCC 25486, S. violaceoruber Tu22, S. anfibioticus ATCC l1891, and S. griseus IFO 13350. In vitro plate assays showed that the addition of 100 $\mu$M tZR increased the growth inhibition of Pseudomonas syringae pv. syringae, a plant pathogen, by S. griseus, a streptomycin producer. We suggest that cytokinin could act as a signaling molecule for antibiotic production in streptomycetes, a group of rhizosphere bacteria.

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References

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