Transactions of the Korean Society of Machine Tool Engineers (한국공작기계학회논문집)

The Korean Society of Manufacturing Technology Engineers (한국생산제조학회)
권호 표지

The Evaluation of Performance of C-11 Radio Isotope Gas Target using Finite Element Method

FEM을 이용한 C-11 동위원소 기체표적의 성능평가

  • 오환섭 (경희대학교 기계공학과) ;
  • 허민구 (경희대학교 대학원 기계공학과) ;
  • 박상필 (경희대학교 대학원 기계공학과) ;
  • 정효진 (경희대학교 대학원 기계공학과)
  • Published : 2006.06.01
Download PDF
⟨ Previous Next ⟩

Abstract

The energy degrader is the most fragile part of the security of a target, has been newly designed to improve the performance of the gas target. Also, the numerical analysis of the heat movement and mechanical movement during the operation of the target has been accomplished. The heat analysis and structure analysis which are using the cooling water flow and pressure in the energy degrader and the finite element analysis program, has been considered with the heat movement and mechanical movement according to the current capacity of proton beam which determines the production yield of the radioactive isotope. Also the possible use range has been determined and at the same time the most suitable running condition according to the current capacity of proton beam has been suggested.

Keywords

References

  1. Mishani, E., 2004, 'Novel carbon-11 labeled 4-dimethylnitrosamine-but-2-enol acid [4-(phenylalanine)- quinacrine-6-yl] - amides : potential PET bio-phores for molecular imaging of EGFR-positive tumors,' Nuclear Medicine and Biology, Vol. 31, pp. 469-476 https://doi.org/10.1016/j.nucmedbio.2003.12.005
  2. Wiebe, L. I., 2004, 'PET radio-pharmaceuticals for metabolic imaging in oncology,' International Congress Series, Vol. 1264, pp. 53-76 https://doi.org/10.1016/j.ics.2003.12.102
  3. Moerlein, S. M., 2002, 'Robotic preparation of Sodium Acetate C 11 Injection for use in clinical PET,' Nuclear Medicine and Biology, Vol. 29, pp. 613-621 https://doi.org/10.1016/S0969-8051(02)00307-4
  4. Mishani, E., 2002, 'Improved method for the quality assurance of (C-11)choline,' Nuclear Medicine and Biology, Vol. 29, pp. 359-362 https://doi.org/10.1016/S0969-8051(01)00311-0
  5. Mishani, E., 1999, 'Radiation levels in cyclotronradiochemistry facility measured by a novel comprehensive -computerized monitoring system,' Nuclear Instruments and Methods in Physics Research Section A, Vol. 425, pp. 332-342 https://doi.org/10.1016/S0168-9002(98)01407-7
  6. Grierson, J. R., 1993, 'Radio-synthesis Of 6-[C-11] D-glucose,' Applied Radiation and Isotopes, Vol. 44, pp 1449-1458 https://doi.org/10.1016/0969-8043(93)90098-U
  7. Kelderman, P., 1984, 'Sediment-water exchange in Lake Grevelingen under different environmental conditions,' Netherlands Journal of Sea Research, Vol. 18, pp. 286-311 https://doi.org/10.1016/0077-7579(84)90007-3
  8. Chohen, M. B., 1977, 'Acute distribution of various C-14 compounds in mice as determined by whole-body auto-radiography: Adjunct for radio-pharmaceutical synthesis,' The International Journal of Applied Radiation and Isotopes, Vol. 28, pp. 286-311
  9. Perris, A. G. and Lane, R. O., 1974, -The production of carbon-11 for medical uses by a Tandem Van de Graff accelerator by theorization 11B(p, n)11C,' The International Journal of Applied Radiation and Isotopes, Vol. 25, pp. 19-23 https://doi.org/10.1016/0020-708X(74)90049-0
  10. Winstead, M.. B., 1969, 'The use of sodium TIC-benzoate in renal visualization,' The International Journal of Applied Radiation and Isotopes, Vol. 20, pp. 859-862 https://doi.org/10.1016/0020-708X(69)90111-2
  11. Oh, H. S., Kim, S .J. and Kim, D. H., 2001, 'Analysis of Thermal Stresses in the Interface of Brazing Welded with Dissimilar Materials by BEM,' Proceeding of the KSMTE Autumn Conference, pp. 269-274
  12. Hur, M. G., Oh, H. S., Park, S. P., Jung H. J. and Yang S. D., 2005, 'Strength Evaluation of C-11 Radio Isotope Gas Target using Finite Element Method,' Proceeding of the KSPE Spring Conference, pp. 233