Asian-Australasian Journal of Animal Sciences

  • 제19권9호
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  • Pages.1342-1346
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  • 2006
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  • 1011-2367(pISSN)
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  • 1976-5517(eISSN)
아세아태평양축산학회 (Asian Australasian Association of Animal Production Societies)
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Prevalence of Fimbrial Antigen (K88 variants, K99 and 987P) of Enterotoxigenic Escherichia Coli from Neonatal and Post-weaning Piglets with Diarrhea in Central China

  • Wang, J. (Key Laboratory of Swine Breeding and Genetics of Agricultural Ministry, College of Animal Scince Huazhong Agricultural University) ;
  • Jiang, S.W. (Key Laboratory of Swine Breeding and Genetics of Agricultural Ministry, College of Animal Scince Huazhong Agricultural University) ;
  • Chen, X.H. (Key Laboratory of Swine Breeding and Genetics of Agricultural Ministry, College of Animal Scince Huazhong Agricultural University) ;
  • Liu, Z.L. (Key Laboratory of Swine Breeding and Genetics of Agricultural Ministry, College of Animal Scince Huazhong Agricultural University) ;
  • Peng, J. (Key Laboratory of Swine Breeding and Genetics of Agricultural Ministry, College of Animal Scince Huazhong Agricultural University)
  • 투고 : 2005.07.17
  • 심사 : 2005.12.13
  • 발행 : 2006.09.01
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초록

Enterotoxigenic Escherichia coli is a major cause of diarrhea in neonatal and post-weaning piglets. To determine the most common fimbrial antigens of ETEC in piglets with diarrhea, two investigations were carried out on intensive pig farms in Hubei province, central China. In 2002-2003, 227 fecal samples from neonatal and post-weaning piglets with diarrhea were tested for the presence of the fimbrial antigen K88 and K99 of ETEC by the polymerase chain reaction (PCR). Twenty-three (10.1%) of 227 fecal samples were found to contain fimbrial antigen K88, which was identified as K88ac variant; and 13 (5.7%) samples containing K99. In 2004, another 179 fecal samples from diarrheic piglets, 1 day to 6 weeks of age, were tested for prevalence of fimbrial antigen K88, K99 and 987P. Forty-seven (26.3%) of the 179 samples carried at least one of the ETEC fimbrial antigens. K88 antigen was detected in 20.1%. In the 36 samples known to carry fimbrial antigen K88, 32 (88.9%) contained K88ad; and 4 (11.1%) contained K88ac; none of them carried K88ab. Fimbrial antigens K99 and 987P were detected in 1.1% and 6.1%, respectively. Our data indicate that K88 is the most common fimbrial antigen of ETEC associated with diarrhea in piglets in Central China.

키워드

참고문헌

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  4. Variation in 12 porcine genes involved in the carbohydrate moiety assembly of glycosphingolipids does not account for differential binding of F4 Escherichia coliand their fimbriae vol.15, pp.1, 2014, https://doi.org/10.1186/s12863-014-0103-x
  5. Refined Candidate Region for F4ab/ac Enterotoxigenic Escherichia coli Susceptibility Situated Proximal to MUC13 in Pigs vol.9, pp.8, 2014, https://doi.org/10.1371/journal.pone.0105013
  6. F4+ ETEC infection and oral immunization with F4 fimbriae elicits an IL-17-dominated immune response vol.46, pp.1, 2015, https://doi.org/10.1186/s13567-015-0264-2
  7. Identification and Screening of Gene(s) Related to Susceptibility to Enterotoxigenic Escherichia coli F4ab/ac in Piglets vol.21, pp.4, 2006, https://doi.org/10.5713/ajas.2008.70464
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