KSBB Journal

The Korean Society for Biotechnology and Bioengineering (한국생물공학회)
권호 표지

Determination of Biological kinetic Parameters for Pharmaceutical Wastewater

제약 폐수의 생물학적 동력학 계수 측정

  • Lee Young-Rak (Department of Chemical and Biomolecular Engineering, Sogang University) ;
  • Choi Kwang-Keun (Department of Chemical and Biomolecular Engineering, Sogang University) ;
  • Lee Jin-Won (Department of Chemical and Biomolecular Engineering, Sogang University)
  • 이영락 (서강대학교 화공생명공학부) ;
  • 최광근 (서강대학교 화공생명공학부) ;
  • 이진원 (서강대학교 화공생명공학부)
  • Published : 2006.02.01
Download PDF
⟨ Previous Next ⟩

Abstract

The aim of this research is to estimate the values of biological kinetic parameters of pharmaceutical wastewater for understanding biochemical properties. Maximum specific growth rate (${\mu}m$), yield coefficient (Y), and half-velocity coefficient (KS) were determined using oxygen uptake rate (OUR), and the results were 10.49/day (0.437/hr), 0.655, and 38.89 mg/L, respectively. Measured ${\mu}max$ by nonlinear regression of Monod equation was 10.63/day (or 0.443/hr), and this value was similar with above result. These parameters may be used to increase efficiency of pharmaceutical wastewater treatment and to determine amount of oxygen needed to removal BOD and dissolved oxygen in activated sludge process.

본 연구는 다양한 유기물과 난분해성 물질들이 포함되어 있는 제약 폐수 내 미생물의 생화학적 특성을 이해하고자 생물학적 동력학 계수를 측정 하고자하였다. 생물학적 동력학 계수는 최대 비성장율과 수율계수, 그리고 반속도상수를 측정하였는데, 각각 10.49/day (0.437/hr), 0.655 그리고 38.89 mg/L로 나타났다. Monod 식의 비선형회귀분석으로 구한 ${\mu}_{max}$ 값 또한 10.63/day (0.443/hr)로 측정되어 두가지 경우에서 구한 값이 유사함을 알 수 있었다. 이러한 생물학적 동력학 계수를 제약 폐수 처리의 활성슬러지 공정의 산소요구량 및 용존 산소 농도 연구와 병행한다면 제약 폐수의 처리 효율 증진 효과를 기대할 수 있을 것으로 판단된다.

Keywords

References

  1. Kappler, J. and W. Gujer (1992), Estimation of kinetic parameters of heterotrophic biomass under aerobic conditions and characterization of wastewater of activated sludge modelling, Wat. Sci. Tech. 25, 125-139
  2. Green, M. and G. Shelef (1981), Sludge viability in a biological reactor, Wat. Res. 15, 953-959 https://doi.org/10.1016/0043-1354(81)90202-5
  3. Speitel Jr., G. E. and F. A. DiGiano (1988), Determination of microbial kinetic coefficients through measurement of initial rates by radiochemical techniques, Wat. Res. 22, 829-835 https://doi.org/10.1016/0043-1354(88)90020-6
  4. Jorgensen, P. E., T. Eriksen, and B. K. Jensen (1992), Estimation of viable biomass in wastewater and activated sludge by determination of ATP, oxygen utilization rate and FDA hydrolysis, Wat. Res. 1495-1501 https://doi.org/10.1016/0043-1354(92)90069-G
  5. Henze, M., C. P. L. Grady, M. Gujer, G. V. R. Marais, and T. Matsuo (1987), Activated Sludge No. 1, IAWPRC Scietific and Technical Report No. 1, IAWPRC, London
  6. Sollfrank, U. and W. Gujer (1990), Simultaneous determination of oxygen uptake rate and oxygen transfer coefficient in activated sludge systems by an on-line method, Wat. Res. 24, 725-732 https://doi.org/10.1016/0043-1354(90)90028-5
  7. Ekama, G. A., P. L. Dold, and G. V. R. Marais (1986), Procedures for determining influent COD fractions and the maximum specific growth rate of heterotrophs in a activated sludge systems, Wat. Sci. Tech. 18, 91-114
  8. Lee, Y. R., G. Y. Lee, J. H. Lim, S. H. Lee, H. M. Moon, S. J. Sim, and J. W. Lee (2001), Measurement of Biological Activity in Pharmaceutic Wastewater by Using Respirometer, Korean J. Biotechnol. Bioeng. 16, 183-187
  9. Samuel, D., R. Suman, and Anjaneyulu Y. (2005), Evaluation of biokinetic parameters for pharmaceutical wastewaters using aerobic oxidation integrated with chemical treatment, Process biochemistry 40, 165-175 https://doi.org/10.1016/j.procbio.2003.11.056
  10. Lenore, S. C., E. G. Arnold, and D. E. Andrew (1995), Standard Methods for the examination of water and wastewater 20th ed., APHA, AWWA, WEF
  11. Choung, Y. K., H. S. Kim, and S. I. Yoo (2000), The estimation of Bio-kinetic parameters using respirometric analysis, J. KSEE. 22, 11-19
  12. Alan, F. R. and F. G. Anthony (1992), Design and operation of activated sludge processes using respirometry, Lewis Publishers, 77-96
  13. Shuler, M. L. and F. Kargi (1992), Bioprocess Engineering, PTR Prentice-Hall, Inc., 148-194
  14. Porge, N., L. Jascewicz, and S. Hoover (1956), Biological Treatment of Sewage and Industrial Wastes, Reinhold, New York, 25-48