The Journal of the Society of Stroke on Korean Medicine (대한중풍순환신경학회지)

The Society of Stroke on Korean Medicine (대한중풍순환신경학회)
권호 표지

Effects of Uwhangchungsimwon on Arterial Stiffness

우황청심원이 정상인의 동맥경직도에 미치는 영향

  • Rhee, Jun-woo (Department of Oriental internal medicine, College of Medicine, Pochun CHA University) ;
  • Moon, Sang-kwan (Department of Cardiovascular and Neurologic Diseases(Stroke Center) College of Oriental Medicine, Kyung-Hee University) ;
  • Park, Seong-uk (Department of Cardiovascular and Neurologic Diseases(Stroke Center) College of Oriental Medicine, Kyung-Hee University) ;
  • Jung, Woo-sang (Department of Cardiovascular and Neurologic Diseases(Stroke Center) College of Oriental Medicine, Kyung-Hee University) ;
  • Park, Jung-mee (Department of Cardiovascular and Neurologic Diseases(Stroke Center) College of Oriental Medicine, Kyung-Hee University) ;
  • Ko, Chang-nam (Department of Cardiovascular and Neurologic Diseases(Stroke Center) College of Oriental Medicine, Kyung-Hee University) ;
  • Cho, Ki-ho (Department of Cardiovascular and Neurologic Diseases(Stroke Center) College of Oriental Medicine, Kyung-Hee University) ;
  • Bae, Hyung-sup (Department of Cardiovascular and Neurologic Diseases(Stroke Center) College of Oriental Medicine, Kyung-Hee University) ;
  • Kim, Young-suk (Department of Cardiovascular and Neurologic Diseases(Stroke Center) College of Oriental Medicine, Kyung-Hee University)
  • 이준우 (포천중문의과대학교 분당차한방병원 내과) ;
  • 문상관 (경희대학교 한의과대학 2내과학교실) ;
  • 박성욱 (경희대학교 한의과대학 2내과학교실) ;
  • 정우상 (경희대학교 한의과대학 2내과학교실) ;
  • 박정미 (경희대학교 한의과대학 2내과학교실) ;
  • 고창남 (경희대학교 한의과대학 2내과학교실) ;
  • 조기호 (경희대학교 한의과대학 2내과학교실) ;
  • 배형섭 (경희대학교 한의과대학 2내과학교실) ;
  • 김영석 (경희대학교 한의과대학 2내과학교실)
  • Published : 2006.12.01
Download PDF
⟨ Previous Next ⟩

Abstract

Objectives : Uwhangchungsimwon (UC) is one of the famous herbal medicine frequently used for stroke, hypertension, and atherosclerosis, etc. Therefore, we intended to examine if UC could have therapeutic effect on arterial stiffness by assessing Cardio-Ankle Vascular lndex (CAVI). Methods : We enrolled 38 healthy male subjects (28±4.41 years old) and divided them into two groups (UC and control group). The UC group (N=22) were treated with 1 pill of UC and monitored by CAVI every hour for 6 hours. The control group(N=16) did not receive any medicine and were also monitored by CAVI the same manner as the UC group. In both group, we also assessed each subject's Yin-Yang pattern score by the diagnostic scoring system. In analysis, we compared the difference of CAVIs between the UC and the control group considering subject's Yin-Yang pattern. Results : There was no significant difference in the change of CAVI between the UC and the control group. After excluding Yang-pattern subjects in both group, however, we could observe that CAVI decreased significantly 5 hours after UC administration compared with the corresponding CAVI in the control group (P=0.025). In the repeated measure analysis, the between-subjects effect had statistical significance (P=0.035). Conclusion : According to these results, we suggest that UC have therapeutic effect on arterial stiffness especially after taking oriental medical diagnosis into consideration.

Keywords