References
- Astrup, T. and S. Mullertz. 1952. The fibrin plate method for estimating fibrinolytic activity. Arch. Biochem. Biophys. 40: 346-351 https://doi.org/10.1016/0003-9861(52)90121-5
- Bradford, M. M. 1976. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72: 248-254 https://doi.org/10.1016/0003-2697(76)90527-3
- Chihara, G., J. Hamuro, Y. Y. Maeda, Y. Arai, and F. Fukuoka. 1970. Fractionation and purification of the polysaxccharides with marked antitumor activity, especially lentinan, from Lentinus edodes (Berk.) Sing. (an edible mushroom). Cancer Res. 30: 2776-2781
- Choi, H. S. and H. H. Shin. 1998. Purification and partial characterization of a fibrinolytic protease in Pleurotus ostreatus. Mycologia 90: 674-679 https://doi.org/10.2307/3761226
- Choi, N. S., K. H. Yoo, J. H. Hahm, K. S. Yoon, K. T. Chang, B. H. Hyun, P. J. Maeing, and S. H. Kim. 2005. Purification and characterization of a new peptidase, bacillopeptidase DJ-2, having fibrinolytic activity, produced by Bacillus sp. DJ-2 from Doen-Jang. J. Microbiol. Biothecnol. 15: 72-79
- Choi, W. A., J. W. Lee, K. H. Lee, and S. H. Park. 1998. Effects of environmental and nutritional conditions on fibrinolytic enzyme production from Bacillus subtilis BK-17 in flask culture. Kor. J. Biotechnol. Bioeng. 13: 491-496
- Collens, D. and H. R. Lijnen.1991. Basic and clinical aspects of fibrinolysis and thrombosis. Blood 78: 3114-3124
- Fujita, M., K. Nomura, K. Hong, Y. Ito, A. Asada, and S. Nishimuro. 1993. Purification and characterization of strong fibrinolytic enzyme (nattokinase) in the vegetable cheese natto, a popular soybean fermented food in Japan. Biochem. Biophy. Res. Commun. 197: 1340-1347 https://doi.org/10.1006/bbrc.1993.2624
- Harlan, J. M. and L. A. Harker. 1981. Haemostasis, thrombosis and thromboembolic disorder. Med. Clin. North Am. 65: 855-857 https://doi.org/10.1016/S0025-7125(16)31502-4
- Jang, J. S., D. O. Kang, M. J. Chun, and S. M. Byun. 1992. Molecular cloning of a subtilisin J gene from Bacillus stearothermophilus and its expression in Bacillus subtilis. Biochem. Biophys. Res. Commun. 184: 277-282 https://doi.org/10.1016/0006-291X(92)91189-W
- Jain, S. C., U. Shinde, Y. Li, M. Inouye, and H. M. Berman. 1998. The crystal structure of an autoprocessed Ser221 Cys-subtilisin E propeptide complex at 2.0-A resolution. J. Mol. Biol. 284: 137-144 https://doi.org/10.1006/jmbi.1998.2161
- Kim J. H. and Y. S. Kim. 1999. A fibrinolytic metalloprotease from the fruiting bodies of an edible mushroom, Armillariella mellea. Biosci. Biotechnol. Biochem. 63: 2130-2136 https://doi.org/10.1271/bbb.63.2130
- Kim J. H. and Y. S. Kim. 2001. Characterization of a metallaloenzyme from a wild mushroom, Tricholoma saponaceum. Biosci. Biotechnol. Biochem. 65: 356-362 https://doi.org/10.1271/bbb.65.356
- Kim, W. K., K. H. Choi, Y. T. Kim, H. H. Park, J. Y. Choi, Y. S. Lee, H. I. Oh, I. B. Kwon, and S. Y. Lee. 1996. Purification and characterization of a fibrinolytic enzyme produced from Bacillus sp. strain CK11-4 screened from Chungkook-Jang. Appl. Environ. Microbiol. 62: 2482-2488
- Kweon, M. H., H. Jang, W. J. Lim, H. I. Chang, C. W. Kim, H. C. Yang, H. J. Hwang, and H. C. Sung. 1999. Anticomplementary properties of polysaccharides isolated from fruit bodies of mushroom Pleurotus ostreatus. J. Microbiol. Biotechnol. 9: 450-456
- Laemmli, U. K. 1970. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature (London) 227: 680-685 https://doi.org/10.1038/227680a0
- Lee, J. H., S. M. Cho, H. M. Kim, N. D. Hong, and I. D. Yoo. 1997. Immunostimulating activity of polysaccharides from mycelia of Phellinus linteus grown under different culture conditions. J. Microbiol. Biotechnol. 7: 52-55
- Lee, J. S., H. S. Baik, and S. S. Park. 2002. Optimal production and characterization of fibrinolytic enzymes from Fomitella fraxinea mycelia. Kor. J. Microbiol. Biotechnol. 30: 325- 331
- Lee, S. K., D. H. Bae, T. J. Kwon, S. B. Lee, H. H. Lee, J. H. Park, S. Heo, and M. G. Jhonson. 2001. Purification and characterization of a fibrinolytic enzyme from Bacillus sp. KDO-13 isolated from soybean paste. J. Microbiol. Biotechnol. 11: 845-852
- Lee, S. Y., J. S. Kim, J. E. Kim, K. Sapkota, M. H. Shen, S. Kim, H. S. Chun, J. C. Yoo, H. S. Choi, M. K. Kim, and S. J. Kim. 2005. Purification and characterization of fibrinolytic enzyme from cultured mycelia of Armillaria mellea. Protein Expr. Purif. 43: 1-7 https://doi.org/10.1016/j.pep.2005.03.016
- Liu, K. L., L. X. Du, F. P. Lu, X. Q. Zheng, and J. Xiao. 2005. Purification and characterization of a novel fibrinolytic enzyme from Rhizopus chinensis 12. Appl. Microbiol. Biotechnol. 67: 209-214 https://doi.org/10.1007/s00253-004-1846-5
- Nakajima, N., N. Taya, and H. Sumi. 1993. Potent fibrinolytic enzyme from the lysate of Katsuwonus pelamis digestive tract (Shiokara): Purification and characterization. Biosci. Biotechnol. Biochem. 57: 1604-1605 https://doi.org/10.1271/bbb.57.1604
- Nakamura, T., Y. Yamafata, and E. Ichishima. 1992. Nucleotide sequence of the subtilisin NAT gene, aprN of Bacillus subtilis(natto). Biosci. Biotechnol. Biochem. 56: 1869-1871 https://doi.org/10.1271/bbb.56.1869
- Nonaka, T., H. Ishikawa, Y. Tsumuraya, Y. Hashimoto, and N. Dohmae. 1995. Characterization of a thermostable lysine-specific metallopeptidase from the fruiting bodies of a Basidiomycete Grifola frondosa. J. Biochem. 118: 589-593
- Park, S. S., J. S. Lee, K.G. Bae, K. H. Yu, H. C. Han, and T. J. Min. 2001. Antioxidative activity and structural analysis of the steroid compound from Fomitella fraxinea. Kor. J. Mycol. 29: 67-71
- Paik, H. D., S. K. Lee, S. Heo, S. Y. Kim, H. H. Lee, and T. J. Kwon. 2004. Purification and characterization of the fibrinolytic enzyme produced by Bacillus subtilis KCK-7 from Chungkookjang. J. Microbiol. Biotechnol. 14: 829- 835
- Reed, G. L., L. F. Parhami-Seren, and P. Kussie. 1995. Identification of plasminogen binding region in streptokinase that is necessary for the creation of functional streptokinase-plasminogen activator complex. Biochemistry 34: 10266- 10271 https://doi.org/10.1021/bi00032a021
- Shin, H. H. and H. S. Choi. 1999. Purification and characterization of metalloenzyme from Pleurotus sajor-caju. J. Microbiol. Biotechnol. 9: 675-678
- Sumi, H., H. Hamada, K. Nakashini, and H. Hiratani. 1990. Enhancement of the fibrinolytic activity in plasma by oral administration of nattokinase. Acta Haematol. 84: 139-143 https://doi.org/10.1159/000205051
- Sumi, H., H. Hamada, H. Tsushima, H. Mihara, and H. Muraki. 1987. A novel fibrinolytic enzyme (nattokinase) in the vegetable cheese natto; a typical and popular soybean food in the Japanese diet. Experientia 43: 1110-1111 https://doi.org/10.1007/BF01956052
- Voet, D. and J. G. Voet. 1990. Biochemistry, pp. 1087-1095, 2nd Ed. John Willey and Sons, New York, U.S.A
- Yoshimoto, T., H. Oyama, T. Honda, H. Takeshita, T. Kamiyama, and D. Tsuru. 1988. Cloning and expression of subtilisin amylosacchariticus gene. J. Biochem. 103: 1060- 1065 https://doi.org/10.1093/oxfordjournals.jbchem.a122380
- Zaworski, P. G., K. R. Marotti, V. MacKay, C. Yip, and G. S. Gill. 1989. Production and secretion of porcine urokinase in Saccharomyces cerevisiae: Characterization of the secreted gene product. Gene 28: 545-551