Four cases of gastric submucosal mass suspected as anisakiasis

  • Published : 2006.03.01

Abstract

Anisakiasis is a parasitic disease caused by ingestion of raw fish infected with anisakid larvae. Endoscopic changing patterns of submucosal lesions in chronic gastric anisakiasis have not been known yet. Here we report 4 cases of suspected gastric anisakiasis which were improved during follow-up periods without surgical treatment. The patients presented with abdominal pain, nausea and vomiting after consuming raw marine fish, and visited our gastroenterology outpatient department. Their endoscopic findings showed firm and yellowish submucosal masses accompanied with eccentric erosions. Histologic findings showed severe eosinophilic infiltrations. In blood tests, peripheral eosinophil counts and total IgE levels were elevated. We believed that all cases were caused by larval anisakid infections. The submucosal mass lesions disappeared during the follow-up periods of 2 to 4 mo.

Keywords

References

  1. Alonso-Gomez A, Moreno-Ancillo A, Lopez-Serrano MC, Suarez-de-Parga JM, Daschner A, Caballero MT, Barranco P, Cabanas R (2004) Anisakis simplex only provokes allergic symptoms when the worm parasitises the gastrointestinal tract. Parasitol Res 93: 378-384
  2. Caballero ML. Moneo I (2002) Specific IgE determination to Ani s 1, a major allergen from Anisakis simplex, is a useful tool for diagnosis. Ann Allergy Asthma Immunol 89: 74-77 https://doi.org/10.1016/S1081-1206(10)61914-X
  3. Castan B, Borda F, Inarrairaegui M, Pastor G, Vila J, Zozaya JM (2002) Digestive anisakiasis: clinical manifestations and diagnosis according to localization. Rev Esp Enferm Dig 94: 463-472
  4. Dziekonska-Rynko J, Rokicki J, Jablonowski Z (1997) Influence of infection with III larval stage of Anisakis simplex on the activity of proteases in alimentary tract of guinea pigs. Wiad Parazytol 43: 425-430
  5. Dziekonska-Rynko J, Rokicki J, Jablonowski Z (2002) Effects of ivermectin and albendazole against Anisakis simplex in vitro and in guinea pigs. J Parasitol 88: 395-398 https://doi.org/10.1645/0022-3395(2002)088[0395:EOIAAA]2.0.CO;2
  6. Im KI, Shin HJ, Kim BH, Moon SI (1995) Gastric anisakiasis cases in Cheju-do, Korea. Korean J Parasitol 33: 179-186 https://doi.org/10.3347/kjp.1995.33.3.179
  7. Kim CH, Chung BS, Moon YI, Chun SH (1971) A case report on human infection with Anisakis sp. in Korea. Koeran J Parasitol 9: 39-43 https://doi.org/10.3347/kjp.1971.9.1.39
  8. Ko GH, Park CK, Kong HJ, Choi CS, Lee SH, Hong SJ (1988) Intestinal anisakiasis. Korean J Pathol 22: 154-158
  9. Kojima K (1966) Parasitic granuloma with special reference to histopathological findings of the Anisakis-like larva infection. Jap J Parasitol 15: 30-31
  10. Lee HS, Park KS, Jung KT, Yoo SJ, Kho JH, Park PS, Choi WS, Choi DY, Choi HS (1993) A Case of chronic gastric anisakiasis with massive bleeding. Korean J Gastrointest Endosc 13: 697-700
  11. Lee MS, Kim YS, Kang JH, Park EJ, Cho YB, Sim CS (1999) 2 Cases of submucosal tumors caused by gastric anisakiasis. Korean J Gastrointest Endosc 19: 67-72
  12. Lee KH, Koo JT, Song JH, Hyun MS, Jhi CJ (1981) Acute gastric anisakiasis - endoscopic, radiologic diagnosis and its management. Korean J Intern Med 24: 1220-1227
  13. Moore DA, Girdwood RW, Chiodini PL (2002) Treatment of anisakiasis with albendazole. Lancet 360: 54 https://doi.org/10.1016/S0140-6736(02)09333-9
  14. Seol SY, Ok SC, Pyo JS, Kim IH, Lee SH, Chung JM, Choi HJ, Jeong SJ, Sohn WM (1994) Twenty cases of gastric anisakiasis caused by Anisakis type I larva. Korean J Gastroenterol 26: 17-24
  15. Shim YR, Kim DS, Lee TS (1995) Ileal anisakiasis: A report of two cases. Korean J Pathol 29: 91-95
  16. Song TJ, Cho SW, Joo KH (1999) Endoscopic findings of aucte gastric anisakiasis - Thirty-nine cases in Inchon City. Korean J Gastrointest Endosc 19: 878-884
  17. Van Thiel PH, Kruipers FC, Roskam TH (1960) A nematoede parasitic to herring, causing acute abdominal syndromes in man. Trop Geogr Med 2: 97-113
  18. Yoon WJ, Lee SM, Lee SH, Yoon YB (2004) Gastric anisakiasis. Gastrointest Endosc 59: 400 https://doi.org/10.1016/S0016-5107(03)02591-4