한국임상수의학회지 (Journal of Veterinary Clinics)

  • 제23권3호
  • /
  • Pages.329-333
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  • 2006
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  • 1598-298X(pISSN)
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  • 2384-0749(eISSN)
한국임상수의학회 (The Korean Society of Veterinary Clinics)
권호 표지

져먼 셰퍼드종 개에서 발생한 유전성 악성 심실성 부정맥증

Inherited Malignant Ventricular Tachyarrhythmia in a German Shepherd

  • 이준석 (강원대학교 수의(학부)대학 소동물 내과교실) ;
  • 이승곤 (강원대학교 수의(학부)대학 소동물 내과교실) ;
  • 박인철 (강원대학교 수의(학부)대학 방사선 교실) ;
  • 현창백 (강원대학교 수의(학부)대학 소동물 내과교실)
  • Lee, Joon-Seok (Section of Internal Medicine, School of Veterinary Medicine, Kangwon National University) ;
  • Lee, Seung-Gon (Section of Internal Medicine, School of Veterinary Medicine, Kangwon National University) ;
  • Park, In-Chul (Section of Diagnostic Imaging, School of Veterinary Medicine, Kangwon National University) ;
  • Hyun, Chang-Baig (Section of Internal Medicine, School of Veterinary Medicine, Kangwon National University)
  • 발행 : 2006.09.30
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초록

9살령 수컷 져먼 세퍼드종 개가 주기적인 실신 증상으로 내원하였다. 신체 검사, 혈액 생화학 검사 및 진단영상학 검사에서 특별한 이상 소견은 관찰되지 않았다. 실신 직후 실시한 12-lead심전도에서 환견은 심실조기박동을 동반한 악성 심실성 빈맥(torsade depointes)소견이 관찰되었다. Lidocaine정맥주사 후 심실성 부정맥의 빈도수는 감소되었다. 병력과 심전도 검사(event recordings)를 토대로 본 증례를 져먼 세퍼드종의 유전성 심실성 부정맥증으로 진단하였다. 환견은 초기에 sotalol 구강투여로 증상이 개선되었지만 한달 후 특별한 증상 없이 급사하였다. 본 증례는 국내에서 최초로 보고된 유전성 악성 심실성 부정맥증이다.

A 9-month-old neutered male German Shepherd dog was referred with the primary complaint of episodic collapse. Apparent abnormal findings were not observed in physical examination, routine biochemistry, and diagnostic imaging studies. In the 12-lead surface ECG after collapse, the dog showed frequent ventricular premature contractions (VPCs) with torsade de pointes. The frequency of VPCs was reduced after lidocaine infusion. Based on the history, findings in event recordings oi the ECG and lidocaine response test, the dog was diagnosed as inherited malignant ventricular tachyarrhythmia. Although the dog was initially responded to oral sotalol therapy, the dog was died suddenly. This report described the first case of malignant ventricular tachyarrhythmia of German Sheperd in Korea.

키워드

참고문헌

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