한국임상수의학회지 (Journal of Veterinary Clinics)

  • 제23권3호
  • /
  • Pages.223-229
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  • 2006
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  • 1598-298X(pISSN)
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  • 2384-0749(eISSN)
한국임상수의학회 (The Korean Society of Veterinary Clinics)
권호 표지

최근 국내발병 개 파보바이러스성 장염에 대한 역학적 조사

Epidemiological Observation on Recent Outbreaks of Canine Parvoviral Enteritis in Korea

  • 정석영 (강원대학교 수의학부대학) ;
  • 김두 (강원대학교 수의학부대학) ;
  • 안소저 (강원대학교 수의학부대학) ;
  • 박선일 (강원대학교 수의학부대학)
  • Jeoung, Seok-Young (School of Veterinary Medicine, Kangwon National University) ;
  • Kim, Doo (School of Veterinary Medicine, Kangwon National University) ;
  • Ahn, So-Jeo (School of Veterinary Medicine, Kangwon National University) ;
  • Pak, Son-Il (School of Veterinary Medicine, Kangwon National University)
  • 발행 : 2006.09.30
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초록

세계적으로 canine parvovirus(CPV) 고역가 백신이 사용된 후 CPV 감염이 효과적으로 관리되고 있지만 국내에서는 아직도 CPV 장염의 발생이 계속되고 있다. 본 연구에서는 2003년 6월부터 2005년 5월까지 CPV 장염으로 확진된 140두를 대상으로 CPV 장염의 역학적 조사와 CPV 장염에 이환된 환축의 생존에 영향을 미치는 역학적 요인들에 대하여 조사하였다. CPV 장염은 6-18주령의 예방접종을 실시하지 않았거나 불완전하게 실시한 개체에서 주로 발생하였다. CPV 장염에 이환된 개 중 암컷의 생존율이 숫컷보다 높았으며, 나이가 많을수록 생존율이 높았다(p<0.05). 그리고 HI 항체가가 낮을수록 폐사율이 높게 나타났다(p<0.05). 주요 임상증상으로 설사, 구토, 기면과 탈수증상이 대부분의 환축에서 나타났다. 최근 국내에서 발생하는 CPV 장염은 CPV에 대한 예방접종의 실패와 CPV 백신에 대한 면역반응이 부적당한 것에 기인하는 것으로 생각되므로 면역이 완전히 형성되기 전의 어린 개들은 CPV에 오염된 환경에 노출되지 않도록 예방관리 하는 것이 중요하다.

Recently canine parvovirus(CPV) enteritis had been controlled successfully by the use of low-passage high titer modified live CPV vaccines. However, outbreaks of CPV enteritis have been continued in Korea. In this study, we carried out epidemiological investigation on the recent outbreaks of CPV enteritis of dogs and determined the potential prognostic factors affecting the survival of dogs. The total of 140 dogs diagnosed for CPV enteritis were statistically analysed. The majority of dogs were from 6 to 18 weeks of age and were not vaccinated or incompletely vaccinated. There were significant difference in the survival rate between male and female dogs with CPV enteritis and among the age groups(p<0.05). Moreover, there was significant difference in the survival rate of dogs between HI titer <80 group and HI titer 160 group(p<0.05). The majority of dogs had a history of diarrhea, vomiting, lethargy and dehydration. It was considered that recent outbreak of CPV enteritis in Korea caused by the failure of vaccination and/or by the inadequate antibody responses to CPV vaccines. Prophylactic measures should include isolation of young dogs from the dog population until the vaccination can be expected to provide protection.

키워드

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