Toxicological Research

Korean Society of Toxicology & Korea Environmental Mutagen Society (한국독성학회)
권호 표지

Neurotropism and Expression Pattern of lacZ Inserted PRV-Bartha in Geniculohypothalamic Tract Tracing

lacZ가 삽입된 PRV-Bartha 종의 신경친화성 및 무릎시상하부로 추적시 발현양상 분석

  • 김진상 (대구대학교 물리치료학과) ;
  • 박은세 (대구대학교 물리치료학과) ;
  • 천송희 (대구대학교 물리치료학과) ;
  • 김민희 (대구대학교 물리치료학과) ;
  • 방현수 (대구대학교 물리치료학과) ;
  • 권영실 (대구대학교 물리치료학과) ;
  • 이봉희 (제주대학교 의과대학 해부학교실) ;
  • 김영철 (계명대학교 공중보건학과)
  • Published : 2006.12.30
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Abstract

To localize the connection between intergeniculate nucleus and suprachisasmatic nucleus through geniculohypothalamic tract in postnatal mongolian gerbil, we injected lacZ inserted PRV-Bartha strain into suprachiasrnatic nucleus and tried to immunostain against it with Rb134 and mouse $anti-{\beta}-galactosidase$. The numbers of immunoreactive neurons in intergeniculate leaflet were $8{\pm}3.2$ in P1 Period, $10{\pm}4.1$ in P3 Period and $13{\pm}6.2$ in P7 Period, and was statistically significant (p<0.05) and had tendency to increase with time consuming. The results showed that intergeniculate leaflet had projected some axons into suprachiasrnatic nucleus through geniculohyptothalamic tract in postnatal mongolian gerbil. But we could not exclude the possibility of direct projections from dorsal and ventral geniculate nuclei into suprachisamatic nucleus completely.

Keywords

References

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