환경위생공학 (Journal of environmental and Sanitary engineering)

대한환경위생공학회 (Korean Society for Environmental Sanitary Engineers)
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복분자 추출물이 티로시나아제 프로모터에 미치는 효과

Effect of Rubus coreanum Extracts on Tyrosinase Promoter

  • 진종언 (동강대학 피부미용과) ;
  • 조남철 (동강대학 호텔조리영양과) ;
  • 김관천 (광주보건대학 환경행정과)
  • Chin, Jong-Eon (Dept. of Cosmetology, Dongkang College) ;
  • Cho, Nam-Chul (Dept. of Hotel Culinary Arts & Nutrition, Dongkang College) ;
  • Kim, Kwan-Chun (Dept. of Environmental Administration, Gwangju Health College)
  • 발행 : 2006.09.30
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초록

To estimate the inhibitory effect of Rubus coreanum extract on melanin biosynthesis, we tested its inhibitory effects on tyrosinase promoter in B16 mouse melanoma cells. Rubus coreanum extract by methanol had inhibitory effect approximately 10% on tyrosinase promoter at $100{\mu}g/mL$. In the MTT assay, the same extract exhibited very low cytotoxicity under $100{\mu}g/mL$. The fractions of methylene chloride, butyl alcohol and water did not showed the inhibitory effect on tyrosinase promoter, but the fraction of ethyl acetate exhibited inhibitory effect approximately 11% at $100{\mu}g/mL$.

키워드

참고문헌

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