Journal of Nutrition and Health

  • 제39권8호
  • /
  • Pages.728-732
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  • 2006
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  • 2288-3886(pISSN)
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  • 2288-3959(eISSN)
한국영양학회 (The Korean Nutrition Society)
권호 표지

고콜레스테롤 식이 투여 흰쥐에서 옥수수 펩타이드 섭취가 혈중 지질 성상에 미치는 효과

Effects of Corn Peptide Consumption on Plasma Lipid Profiles in Cholesterol-Fed Rats

  • 문민선 (이화여자대학교 식품영양학과) ;
  • 이지혜 (이화여자대학교 식품영양학과) ;
  • 이막순 (이화여자대학교 식품영양학과) ;
  • 권인숙 (안동대학교 식품영양학과) ;
  • 정용일 (샘표식품주식회사 기술연구소) ;
  • 이대희 (샘표식품주식회사 기술연구소) ;
  • 김양하 (이화여자대학교 식품영양학과)
  • Moon, Min-Sun (Department of Food and Nutritional Sciences, Ewha Woman University) ;
  • Lee, Ji-Hye (Department of Food and Nutritional Sciences, Ewha Woman University) ;
  • Lee, Mak-Soon (Department of Food and Nutritional Sciences, Ewha Woman University) ;
  • Kwun, In-Sook (Department of Food Science and Nutrition, Andong National University) ;
  • Chune, Yong-Il (Sempio Food Research and Development Center) ;
  • Lee, Dae-Hee (Sempio Food Research and Development Center) ;
  • Kim, Yang-Ha (Department of Food and Nutritional Sciences, Ewha Woman University)
  • 발행 : 2006.12.31
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초록

In this study, the effects of corn peptide consumption on plasma lipid profiles were investigated in high cholesterol diet-fed rats. Male Sprague-Dawley rats (n = 21) were fed with corn peptide-free (control) diet, diets containing 2% or 5% com peptide for 5 weeks. Hypercholesterolemia was induced by adding l% cholesterol and 0.5% cholic acid to all diets. No difference was found in food intake and body weight gain among groups. The corn peptide treated groups showed significant improvement in the plasma level of HDL-cholesterol (p<0.05) compared to the control group, while the plasma total cholesterol and LDL-cholesterol were not affected.5oio corn peptide supplemented diet reduced plasma level of triglycerides (p<0.05) The atherogenic index was decreased in the corn peptide treated groups. These results suggest that consumption of corn peptide may lead to an amelioration of metabolic syndrome as well as a reduction of cardiovascular disease and hyperlipidemia through increasing the level of HDL-cholesterol, and decreasing the level of triglycerides in plasma.

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