Journal of Sericultural and Entomological Science (한국잠사곤충학회지)

Korean Society of Sericultural Science (한국잠사학회)
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Study on the Unsaturated Fatty Acids in the Pupae of Silkworm, Bombyx mori

누에번데기 유래 불포화지방산을 이용한 기능성 효과 시험

  • Kang, Pil-Don (Department of Agricultural Biology, National Institute of Agricultural Science and Technology, RDA) ;
  • Kim, Jin-Won (Department of Agricultural Biology, National Institute of Agricultural Science and Technology, RDA) ;
  • Jung, I-Yeon (Department of Agricultural Biology, National Institute of Agricultural Science and Technology, RDA) ;
  • Kim, Kee-Young (Department of Agricultural Biology, National Institute of Agricultural Science and Technology, RDA) ;
  • Kang, Seok-Woo (Department of Agricultural Biology, National Institute of Agricultural Science and Technology, RDA) ;
  • Kim, Mi-Ja (Department of Agricultural Biology, National Institute of Agricultural Science and Technology, RDA) ;
  • Ryu, Kang-Sun (Department of Agricultural Biology, National Institute of Agricultural Science and Technology, RDA)
  • 강필돈 (농업과학기술원 농업생물부) ;
  • 김진원 (농업과학기술원 농업생물부) ;
  • 정이연 (농업과학기술원 농업생물부) ;
  • 김기영 (농업과학기술원 농업생물부) ;
  • 강석우 (농업과학기술원 농업생물부) ;
  • 김미자 (농업과학기술원 농업생물부) ;
  • 류강선 (농업과학기술원 농업생물부)
  • Published : 2006.06.30
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Abstract

Purification method of unsaturated fatty acid from silkworm pupa has been set up. Over 70% of total fatty acid was unsaturated form. Unsaturated,fatty acid from silkworm pupa improved hyperlipemia in the induced hyperlipemial mice, increased the production of collagen, inhibited the activity of collagenase, and cured the dryness-induced skin very quickly.

누에유래 불포화지방산의 분리법을 확립하여 특허출원 하였다(출원번호 :2004-76364호). 분리 정제된 누에유래 불포화지방산의 비율은 70% 이상이었다. 누에유래 불포화지방산의 기능성을 시험해본 결과, 고지혈증 개선의 효과를 보였고, 피부단백질인 콜라겐 생성을 유의적으로 증가시키며, 콜라겐 분해효소 활성을 유의적으로 억제하였다. 또한, 피부건조증 개선에 빠르고 탁월한 효과가 있었다.

Keywords

References

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