Journal of the Korean Association of Oral and Maxillofacial Surgeons

The Korean Association of Oral and Maxillofacial Surgeons (대한구강악안면외과학회)
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THE THERAPEUTIC EFFECT OF SILVER NANOCRYSTALLINE OINTMENT ON TMJ CAPSULITIS

은 나노 연고가 측두하악관절낭염의 환자의 치료에 미치는 영향에 관한 연구

  • 채창훈 (한림대학교 의과대학 치과학교실) ;
  • 김좌영 (한림대학교 의과대학 치과학교실) ;
  • 김미자 (한림대학교 의과대학 치과학교실) ;
  • 정훈 (정훈치과) ;
  • 김승호 (한국생명공학연구원 공통기기 분석실) ;
  • 오현우 (한국생명공학연구원 공통기기 분석실) ;
  • 김영남 ((주)엔피씨, 사단법인 대한턱관절협회) ;
  • 김영일 ((주)엔피씨, 사단법인 대한턱관절협회) ;
  • 양병호 (한림대학교 의과대학 치과학교실) ;
  • 김성곤 (한림대학교 의과대학 치과학교실)
  • Published : 2006.06.30
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Abstract

The silver nanocrystalline is widely used for biological field because of its biocompatibility and anti-microbial effect. The objective of this study was to evaluate the therapeutic efficacy of the silver nanocrystalline ointment on the temporomandibular joint (TMJ) capsulitis. Total 39 patients were included in this study and all patients were received single topical application of the silver nanocrystalline ointment (group A, n=30) or placebo ointment (group B, n=19). Measured variables were maximum mouth opening (MMO), visual analog scale (VAS) for pain, and VAS for function. In results, we could not assess any therapeutic efficacy of single application in the chronic TMJ capsulitis (p>0.05). However, the single application of silver nanocrystalline ointment showed significant improvement in MMO and VAS for pain compared to placebo effect in the acute TMJ capsulitis (p<0.05). We could not find any complications related to ointment application in both groups. In conclusion, the single application of silver nanocrystalline ointment was effective in improving patient's symptom in acute TMJ capsulitis without any noticing complications.

Keywords

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