YAKHAK HOEJI (약학회지)

The Pharmaceutical Society of Korea (대한약학회)
권호 표지

Protective Effects of the Water Extract of Protaetia brevitarsis Larva Against Carbon Tetrachloride-Induced Toxicity in the Primary Cultures of Adult Rat Hepatocytes

랫드 일차 배양 간세포에서 사염화탄소의 독성에 대한 지잠 물추출물의 보호효과

  • 윤수홍 (대구가톨릭대학교 약학대학) ;
  • 김덕현 (대구가톨릭대학교 약학대학) ;
  • 현선희 (영남대학교 약학대학) ;
  • 이상규 (영남대학교 약학대학) ;
  • 전태원 (영남대학교 약학대학) ;
  • 정태천 (영남대학교 약학대학)
  • Published : 2006.08.31
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Abstract

Protective effects of the water extract of Protaetia brevitarsis larva against $CCl_4-induced$ toxicity were investigated in primary cultures of adult rat hepatocytes. The extract used in these studies contained several minerals, fatty acids and amino acids. Treatment of hepatocyte cultures with the extract provided a significant protection from the increased LDH activity induced by $CCl_4$. The results demonstrated that the extract may have the protective effect against $CCl_4-induced$ toxicity in hepatocyte cultures.

Keywords

References

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