YAKHAK HOEJI (약학회지)

The Pharmaceutical Society of Korea (대한약학회)
권호 표지

Characterization of S. aureus Showing MLS Resistance with Foggy D Shape (fMLS)

안개 D형 저지원을 갖는 MLS 내성 황색 포도상 구균의 분포와 내성 기전

  • Yoon, Eun-Jeong (College of Pharmacy and Research Institute of Pharmaceutical Sciences, Seoul National University) ;
  • Kim, Hyun-Jee (College of Pharmacy and Research Institute of Pharmaceutical Sciences, Seoul National University) ;
  • Kwon, Ae-Ran (College of Pharmacy and Research Institute of Pharmaceutical Sciences, Seoul National University) ;
  • Choi, Sung-Sook (Department of pharmacy, Sahmyook University) ;
  • Shim, Mi-Ja (Department of Life Science, University of Seoul) ;
  • Choi, Eung-Chil (College of Pharmacy and Research Institute of Pharmaceutical Sciences, Seoul National University)
  • 윤은정 (서울대학교 약학대학.종합 약학 연구소) ;
  • 김현지 (서울대학교 약학대학.종합 약학 연구소) ;
  • 권애란 (서울대학교 약학대학.종합 약학 연구소) ;
  • 최성숙 (삼육대학교 약학과) ;
  • 심미자 (서울시립대학교 생명과학과) ;
  • 최응칠 (서울대학교 약학대학.종합 약학 연구소)
  • Published : 2006.06.30
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Abstract

A new type of macrolides, lincosamides and streptogramin B antibiotics (MLS) resistance, showing the characteristic phenotype growing within the inhibition zone area around the clindamycin disk, was identified among clinically isolated Staphylococcus aureus. We named the phenotype as MLS resistance with foggy-D shape (fMLS). The average frequency of MLS isolates was 9%. All of fMLS isolates have only erm(A) for the resistance determinant. The growth pattern of the challenged MLS isolate looks intermediate phase between the patterns of inducible MLS resistance and constitutive MLS resistance.

Keywords

References

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