The Korea Journal of Herbology (대한본초학회지)
- Volume 21 Issue 2
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- Pages.135-142
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- 2006
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- 1229-1765(pISSN)
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- 2288-7199(eISSN)
Inhibition of gene expression and production of iNOS and $TNF-{\alpha}$ in LPS-stimulated microglia by On-Bi-Tang
오령산가온비탕의 BV2에서 LPS로 유도된 nitric oxide 및 $TNF-{\alpha}$ 생성에 미치는 영향
- Son, Hye-Young (Department of Herbology, Internal Medicine, College of Oriental Medicine, Dongguk University) ;
- Kim, Sang-Woon (Department of Herbology, Internal Medicine, College of Oriental Medicine, Dongguk University) ;
- Jung, Sun-Ju (Department of Herbology, Internal Medicine, College of Oriental Medicine, Dongguk University) ;
- Jung, Hyo-Won (Department of Herbology, Internal Medicine, College of Oriental Medicine, Dongguk University) ;
- Yoon, Cheol-Ho (Department of Herbology, Internal Medicine, College of Oriental Medicine, Dongguk University) ;
- Park, Yong-Ki (Department of Herbology, Internal Medicine, College of Oriental Medicine, Dongguk University)
- 손혜영 (동국대학교 한의과대학 본초학교실) ;
- 김상운 (동국대학교 한의과대학 본초학교실) ;
- 정선주 (동국대학교 한의과대학 본초학교실) ;
- 정효원 (동국대학교 한의과대학 본초학교실) ;
- 윤철호 (동국대학교 한의과대학 본초학교실) ;
- 박용기 (동국대학교 한의과대학 본초학교실)
- Published : 2006.06.30
Abstract
Objectives : On-Bi-Tang(OB) has been prescribed Chinese traditional medicine for the treatment of inflammatory disease such as chronic renal failure. In this study, we investigated the anti-inflammatory effect of OB extract in the BV2 murine microglial cells. Methods : After the water extract of OB was treated in BV2 cells, murine microglial line, the cell viability was measured by MTT assay. The production of nitric oxide (NO) and