Cosmeceutical activities and Anti-inflammatory effects of Shell from Persicae semen

도인(桃仁) 껍질의 화장품약리활성 및 항염 효과

  • Joe, Woo-A (Department of Cosmetology Science, Nambu University) ;
  • Jang, Min-Jung (Department of Cosmeceutical Science, Daegu Haany University) ;
  • Cheon, Soon-Ju (Department of Cosmeceutical Science, Daegu Haany University) ;
  • Sung, Ji-Yeun (Department of Cosmeceutical Science, Daegu Haany University) ;
  • Choi, Eun-Young (Department of Cosmeceutical Science, Daegu Haany University) ;
  • Kang, Bo-Yeon (Department of Cosmeceutical Science, Daegu Haany University) ;
  • Jung, Su-Hyun (Department of Cosmeceutical Science, Daegu Haany University) ;
  • Jeung, Yeun-Suck (Department of Genetic Resources Technology, Kyushu University) ;
  • Kim, Young-Sun (LJH Cosmetic Co., Ltd.) ;
  • An, Bong-Jeun (Department of Cosmeceutical Science, Daegu Haany University) ;
  • Lee, Chang-Eon (Department of Cosmeceutical Science, Daegu Haany University) ;
  • Lee, Jin-Tae (Department of Cosmeceutical Science, Daegu Haany University)
  • 조우아 (남부대학교 향장미용학부) ;
  • 장민정 (대구한의대학교 화장품약리학과) ;
  • 천순주 (대구한의대학교 화장품약리학과) ;
  • 성지연 (대구한의대학교 화장품약리학과) ;
  • 최은영 (대구한의대학교 화장품약리학과) ;
  • 강보연 (대구한의대학교 화장품약리학과) ;
  • 정수현 (대구한의대학교 화장품약리학과) ;
  • 정연숙 ;
  • 김영선 ((주) 이지함 코스메틱) ;
  • 안봉전 (대구한의대학교 화장품약리학과) ;
  • 이창언 (대구한의대학교 화장품약리학과) ;
  • 이진태 (대구한의대학교 화장품약리학과)
  • Published : 2006.06.30

Abstract

Objectives : In this paper, we tested the applicability of shell from Persicae semen in cosmetics through cosmeceutical activities including anti-oxidant, tyrosinase inhibition and anti-inflammatory effects. Methods : Persicae semen, which had been extracted, concentrated, and freeze drying with water and ethanol, have been used for the experiment. The effects on electronic donating ability, SOD-like activity, xanthine oxidase inhibition, whitening effect have been investigated in the cosmeceutical activity measurement of function experiment. Results : In the electron donating ability test, 1,000ppm of EPS (ethanol extract of shell from Persicae semen) showed an effect of 87%. SOD-like activities showed 93% at the 10,000ppm of WPS (water extract of shell from Persicae semen). In the xanthine oxidase inhibition test, 1,000ppm of BHA showed an effect of 27%, while EPS showed an effect of 62%. We were able to get an effect of 95% from EPS at 10,000 ppm in the tyrosinase inhibition test. In the anti-inflammatory test, the EPS inhibited the generation of nitric oxide. In the case of the EPS, there were no signs of cytotoxicity against raw 264.7 and anti-inflammatory effects could be identified when the manifestation of iNOS was decreased. Conclusion : Therefore, the EPS has potential as an effective raw materials for cosmetic.

Keywords