Journal of Physiology & Pathology in Korean Medicine (동의생리병리학회지)

The Physiological Society of Korean Medicine and The Society of Pathology in Korean Medicine (대한동의생리학회·한의병리학회)
권호 표지

Experimental Studies on Hair Growth Effect of Extracts of Cortex Mori Radicis in Hair Removed C57BL/6N Mice

상백피(桑白皮) 추출물(抽出物)의 발모효과(發毛效果)에 관한 실험적 연구

  • Na, Hyun-Uk (Department of Pathology, College of Oriental Medicine, Woosuk University) ;
  • Lee, Moon-Won (Department of Anatomy, College of Oriental Medicine, Woosuk University) ;
  • Jeong, Han-Sol (Department of Pathology, College of Oriental Medicine, Woosuk University) ;
  • Kwon, Jin (Department of Prosthetics & Othotics, Korea National College of Rehabilitation & Welfare) ;
  • Lee, Kwang-Gyu (Department of Pathology, College of Oriental Medicine, Woosuk University) ;
  • Lee, Chang-Hyun (Department of Anatomy, College of Oriental Medicine, Woosuk University)
  • 나현욱 (우석대학교 한의과대학 병리학교실) ;
  • 이문원 (우석대학교 한의과대학 해부학교실) ;
  • 정한솔 (우석대학교 한의과대학 병리학교실) ;
  • 권진 (한국재활복지대학 의료보장구과) ;
  • 이광규 (우석대학교 한의과대학 병리학교실) ;
  • 이창현 (우석대학교 한의과대학 해부학교실)
  • Published : 2006.04.25
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Abstract

Cortex Mori radicis has been used as a components of antidiabetics, antiasthma and diuresis in Oriental Medicine. This experiment examined the effect of an extracts, obtained from the acetone(CM-A) and aqueous(CM-W) extracts of Cortex Mori radicis, on hair growing activity of the C57BL/6N mice after topical application to skin. We investigated the number of hair follicle and mast cells, and changes of subpopulation of splenocytes and thymocytes in skin for 16 day. The results were as follows : The Hair growing effect in experimental groups was more increased in 85%(CM-A) and 90%(CM-W) than control group(10%) in hair depilated area. The number of hair follicle in experimental groups(CM-A and CM-W) was more increased than control group. Splenic B/T lymphocytes of CM-A group were decreased compare to control group. CD4/CD8 positive TH cells in splenic T lymphocytes of CM-W group were increased compare to control group. These results suggest that CM-A and CM-W may be used in treatment of alopecia areata.

Keywords

References

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