Journal of Sensor Science and Technology (센서학회지)

The Korean Sensors Society (한국센서학회)
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Fiber-optic biosensor for analysis of glucose and lactate in blood samples

혈액중 포도당과 젖산의 분석을 위한 광섬유 생물센서

  • Sohn, Ok-Jae (Bioprocess Technology Lab., Chonnam National University) ;
  • Rhee, Jong-Il (School of Applied Chemical Engineering, Chonnam National University)
  • 손옥재 (전남대학교 생물공정기술연구실) ;
  • 이종일 (전남대학교 응용화학공학부)
  • Published : 2006.01.31
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Abstract

Optical-fiber sensors have been developed to determine the concentrations of glucose and lactic acid in blood samples. Fluorescence dye [tris(2,2'-biphenyridine)-ruthenium(II)-chloride (RuBPY)] was entrapped by using a silicon to the unclad tip of a glass optic fiber. Enzymes like glucose oxidase (GOD) and lactate oxidase (LOD) have been immobilized by acrylamide resin adhesive, adsorption with zeolite or covalent bonding with aminopropyl-triethoxysilan. The fiber-optic glucose/lactate sensor was then used to analyze the concentrations of glucose and lactate in blood samples. The results were compared with the results of HPLC analysis and their difference was in error by less then 5 %.

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References

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