대한수의학회지 (Korean Journal of Veterinary Research)

  • 제45권3호
  • /
  • Pages.387-390
  • /
  • 2005
  • /
  • 2466-1384(pISSN)
  • /
  • 2466-1392(eISSN)
대한수의학회 (The Korean Society of Veterinary Science)
권호 표지

어린 알라스카 말라무트의 대퇴골에 발생한 골육종

Juvenile osteosarcoma in the femur of an Alaskan malamute

  • 지향 (서울대학교 수의과대학) ;
  • 오상연 (서울대학교 수의과대학) ;
  • 비둘 (서울대학교 수의과대학) ;
  • 김현욱 (해마루 2차 진료동물병원) ;
  • 최지혜 (해마루 2차 진료동물병원) ;
  • 김대용 (서울대학교 수의과대학)
  • Jee, Hyang (Department of Veterinary Pathnology, College of Veterinary Medicine and School of Agricultural Biotechnology, Seoul National Universtiy) ;
  • Oh, Sang yeon (Department of Veterinary Pathnology, College of Veterinary Medicine and School of Agricultural Biotechnology, Seoul National Universtiy) ;
  • Pakhrn, Bidur (Department of Veterinary Pathnology, College of Veterinary Medicine and School of Agricultural Biotechnology, Seoul National Universtiy) ;
  • Kim, Hyun-wook (Haemaru Animal Referral Hospital) ;
  • Choi, Ji-hye (Haemaru Animal Referral Hospital) ;
  • Kim, Dae-yong (Department of Veterinary Pathnology, College of Veterinary Medicine and School of Agricultural Biotechnology, Seoul National Universtiy)
  • 심사 : 2005.08.22
  • 발행 : 2005.09.22
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초록

An 18-month-old male Alaskan malamute was euthanized due to slowly growing mass around the left femur after history of left posterior limb lameness. At necropsy, a firm confluent mass approximately 15cm in diameter was noted surrounding the femur and proximal portion of the tibia/ulna with traumatic ulceration of the overlying skin. On cross sections of the mass, many unencapsulated firm tan coalescing lobules were noted. The neoplasm consisted of closely packed spindle cells with homogenous eosinophilic material (osteoids) between the neoplastic cells. The pulmonary metastasis was confirmed. Based on the gross and histopathologic examinations, the case was diagnosed as juvenile osteosarcoma.

키워드

참고문헌

  1. Bennett D, Campbell JR, Brown P. Osteosarcoma associated with healed fractures. J Small Anim Pract 1979, 20, 13-18 https://doi.org/10.1111/j.1748-5827.1979.tb07016.x
  2. Bleier T, Lewitschek HP, Reinacher M. Canine osteosarcoma of the penile bone. J Vet Med 2003, 50, 397-398 https://doi.org/10.1046/j.0931-184X.2003.00562.x
  3. Brem H, Folkman J. Inhibition of tumor angiogenesis mediated by cartilage. J Exp Med 1975, 141, 427-434 https://doi.org/10.1084/jem.141.2.427
  4. Brodey RS, Rise WH. Canine osteosarcoma:A clinicopathologic study of 194 cases. Clin Orthop 1969, 62, 54-64
  5. Jubb KVF, Kennedy PK, Palmer N. Pathology of domestic animals. 4th ed. pp. 133-135, Academic press, San Diego, 1991
  6. Kirpensteijn J, Kid M, Rutteman R, Reske E. Prognostic significance of a new histologic grading system for canine osteosarcoma. Vet Pathol 2002, 39, 240-246 https://doi.org/10.1354/vp.39-2-240
  7. Levine RA, Fleischli MA. Inactivation of p53 and retinoblastoma family pathways in canine osteosarcoma cell lines. Vet Pathol 2000, 37, 54-61 https://doi.org/10.1354/vp.37-1-54
  8. Misdrop W, Hart AA. Some prognostic and epidemiological factors in canine osteosarcoma. J Natl Cancer Inst 1979, 62, 537-545 https://doi.org/10.1093/jnci/62.3.537
  9. Phillips L, Hager D, Parker R, Yanik D. Osteosarcoma with a pathologic fracture in a six month-old dog. Vet Radiol 1986, 27, 18-19
  10. Prior C, Watrous BJ, Penfolde D. Radial diaphyseal osteosarcoma with associated bone infarction in a dog. J Am Anim Hosp Assoc 1986, 22, 43-48
  11. Spodnick GJ, Berg J, Rand WM, Schelling SH, Couto G, Harvey HJ, Henderson RA, MacEwen G, Mauldin N, McCaw DL. Prognosis for dogs with appendicular osteosarcoma treated by amputation alone. J Am Vet Med Assoc 1992, 200, 995-999