Journal of the Korean Applied Science and Technology (한국응용과학기술학회지)

The Korean Society of Applied Science and Technology (한국응용과학기술학회)
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The Structure Change Study on the Actin-Myosin Cross-Bridges in SH of Myosin Head by The Computer Data

컴퓨터 분석에 의한 Myosin Head의 SH가 Actin-Myosin Cross-Bridges에 따른 구조변화 연구

  • Kim, Duck-Sool (Department of Computer Engineering Tongmyong University of Information Technology) ;
  • Ok, Soo-Yol (Department of Computer Engineering Tongmyong University of Information Technology) ;
  • Park, Keun-Ho (Department of Chemical Engineering, Changwon National University)
  • 김덕술 (동명정보대학교 컴퓨터공학과) ;
  • 옥수열 (동명정보대학교 컴퓨터공학과) ;
  • 박근호 (창원대학교 공과대학 화공시스템공학과)
  • Published : 2005.03.31
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Abstract

IASL(iodo acetamide) and MSL(maleimide) disordered the orderly helix arrangement of myosin in the rest state of spin level. Especially the effect of IASL was great. Equatorial refiection(10,11) change inferred that myosin head was moved to the vicinity of actin filament by spin level. The intensity change of 143${\AA}$ and 72${\AA}$ could offer information of the mass projection of population of myosin heads along the :filament axis. The slope of intensity profile of the mass projection of 143${\AA}$ and reflection of IASL is appeared and that of MSL is appeared sharply. The decrease of 215${\AA}$ reflection intensity is appeared the periodical characteristic of 143${\AA}$ reflection by spin label. The raise of MSL actin reflection at 51${\AA}$ and 59${\AA}$ in the actin reflection change refers that the shifted myosin head binds a certain actin or changes an actin structure by spin label effect. Because iodo acetamide has a tendency to decease the actin reflection, actin dose not bind myosin head. From this result, we could conclude that LASL and MSL are spin labeled on SH of myosin head and disordered the helix arrangement of actin.

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References

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