Clinical and Experimental Reproductive Medicine

The Korean Society for Reproductive Medicine (대한생식의학회)
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The histologic features of the uterus and adnexa extirpated from gender identity disorder patients with depot androgen injection

남성호르몬 투여 받은 성 주체성 장애 환자에서 적출된 자궁 및 부속기의 조직학적 특징에 관한 고찰

  • Byun, Jae Chun (Department of Obstetrics and Gynecology, College of Medicine, Dong-A University) ;
  • Kwak, Bong Gyu (Department of Obstetrics and Gynecology, College of Medicine, Dong-A University) ;
  • Shin, Ji Hyun (Department of Obstetrics and Gynecology, College of Medicine, Dong-A University) ;
  • Cha, Moon Seok (Department of Obstetrics and Gynecology, College of Medicine, Dong-A University) ;
  • Han, Myoung Seok (Department of Obstetrics and Gynecology, College of Medicine, Dong-A University) ;
  • Rha, Seo Hee (Department of Pathology, College of Medicine, Dong-A University) ;
  • Kim, Seok Kwun (Department of Plastic Surgery, College of Medicine, Dong-A University)
  • 변재천 (동아대학교 의과대학 산부인과학교실) ;
  • 곽봉규 (동아대학교 의과대학 산부인과학교실) ;
  • 신지현 (동아대학교 의과대학 산부인과학교실) ;
  • 차문석 (동아대학교 의과대학 산부인과학교실) ;
  • 한명석 (동아대학교 의과대학 산부인과학교실) ;
  • 나서희 (동아대학교 의과대학 해부병리학교실) ;
  • 김석권 (동아대학교 의과대학 성형외과학교실)
  • Published : 2005.12.30
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Abstract

Objective: To investigate the histologic features of the uterus and adnexae extirpated from gender identity disorder (GID) patients that received depot androgen injection. Methods: We reviewed the histologic findings of the uterus and adnexae removed from sixteen GID patients, who had taken depot androgen injection for 5~168 months. Results: Fourteen patients (87.5%) showed the atrophied epithelium of exocervix and all of 16 patients (100%) showed the atrophy of endometrium. Seven patients (43.7%) showed multiple cystic follicles in the ovarian cortex and 6 patients (37.5%), 3 patients (18.7%) showed corpus albicans and corpus luteum, respectively. Conclusions: Exogenous androgen induced atrophy of cervix and endometrium. This effect was more prominent in the endometrium. In addition, PCO-like histologic features were observed in the ovary.

Keywords

Acknowledgement

Supported by : 동아대학교

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