Journal of fish pathology (한국어병학회지)

The Korean Society of Fish Pathology (한국어병학회)
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Mass Mortality Caused by Nocardial Infection in Cultured Snakehead, Channa arga in Korea

Norcardia 감염증에 의한 양식 가물치의 대량 폐사

  • Park, Myoung-Ae (Pathology Team, National Fisheries Research and Development Institute) ;
  • Lee, Deok-Chan (Pathology Team, National Fisheries Research and Development Institute) ;
  • Cho, Mi-Young (Pathology Team, National Fisheries Research and Development Institute) ;
  • Choi, Hee-Jung (Pathology Team, National Fisheries Research and Development Institute) ;
  • Kim, Jin-Woo (Pathology Team, National Fisheries Research and Development Institute)
  • 박명애 (국립수산과학원 병리연구팀) ;
  • 이덕찬 (국립수산과학원 병리연구팀) ;
  • 조미영 (국립수산과학원 병리연구팀) ;
  • 최희정 (국립수산과학원 병리연구팀) ;
  • 김진우 (국립수산과학원 병리연구팀)
  • Published : 20050800
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Abstract

A new disease causing mass mortality of farmed snakehead (Channa arga) has emerged in Korea over the summer of 2005. The affected fish showed no specific external signs with the exception of a distended abdomen and hemorrhaging around the anus. After opening the abdomen, the visceral organs, liver, spleen and kidney, present numerous white nodular structures. Histopathological examination revealed these nodules to be evidence of granulomas in the visceral organs. A Gram-positive, filamentous bacterium was isolated from all of the affected fish. Development of primers for a genus-specific peR assay for Nocardia, following analysis of the sequences of the complete 16S rRNA genes from Nocardia spp. and non-Nocardia bacterial genes, allowed identification of the causative organism as Nocardia. This is the first report of a nocardial infection of fish in Korea.

2005년 여름에 국내에서 사육되는 가물치에서 대량폐사를 수반하는 새로운 질병이 발견되었다. 감염 어류는 복부팽만과 항문 주위 출혈 이외의 특이한 외부 증상을 나타내지 않았으나 복부를 절개하면 많은 수의 백색 결절이 간, 비장 및 신장을 포함한 내부 장기에서 관찰되었다. 특히 내부 장기의 조직병리학적 관찰에서 granuloma가 관찰되었다. 이들 감염 어류에서 Gram 양성의 사상균이 분리되었다. 분리균은 Nocardia spp.와 non-Nocardia 균의 16S rRNA 염기 분석에 기초한 Nocardia 특이 primer를 사용한 PCR 방법으로 확인하였다. 이것은 어류에서 발생한 Nocardia 감염증의 국내 첫 사례이다.

Keywords

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