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The Pharmaceutical Society of Korea (대한약학회)
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Potentially Hepatoprotective Glycolipid Constituents of Lycium chinense Fruits

  • Jung Kiwon (College of Pharmacy and Research Institute of Pharmaceutical Science, Seoul National University) ;
  • Chin Young-Won (College of Pharmacy and Research Institute of Pharmaceutical Science, Seoul National University) ;
  • Kim Young Choong (College of Pharmacy and Research Institute of Pharmaceutical Science, Seoul National University) ;
  • Kim Jinwoong (College of Pharmacy and Research Institute of Pharmaceutical Science, Seoul National University)
  • Published : 2005.12.01
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Abstract

Further investigation of Lycium chinense fruits gave a mixture of (6'-O-palmitoyl)- and (6'-O­stearoyl)-$\beta$-sitosterol-3-O-$\beta$-D-glucopyranoside (1) and two glycolipids, 1-O-(9Z, 12Z, 15Z-octa­decatrienoyl)-2-O-(9Z, 12Z, 15Z-octadecatrienoyl)-3-O-$\beta$-D-galactopyranosyl glycerol (2) and 1-O-(9Z, 12Z-octadecadienoyl)-2-O-(9Z, 12Z, 15Z-octadecatrienoyl)-3-O-$\beta$-D-galactopyranosyl glycerol (3). These compounds were newly isolated as constituents of L. chinense.

Keywords

References

  1. Chaurasia, N. and Wichti, M., Sterols and steryl glycosides from Urtica dioica. J. Nat. Prod., 50, 881-885 (1987) https://doi.org/10.1021/np50053a018
  2. Chin, Y.-W., Lim, S. W., Kim, S.-H., Sin, D.-Y., Sur, Y.-G., Kim, Y. B., Kim, Y. C., and Kim, J., Hepatoprotective pyrrole derivatives of Lycium chinense fruits. Bioorg. Med. Chem. Lett., 13, 79-81 (2003) https://doi.org/10.1016/S0960-894X(02)00846-6
  3. Iribarren, A. M. and Pomilio, A. B., Components of Bauhinia candicans. J. Nat. Prod., 46, 752-752 (1983) https://doi.org/10.1021/np50029a028
  4. Jung, J. H., Lee, H., and Kang, S. S., Diacylglycerylgalactosides from Arisaema amurese. Phytochemistry, 42, 447-452 (1996) https://doi.org/10.1016/0031-9422(95)00929-9
  5. Kadota, S., Lami, N., Tezuka, Y., and Kikuchi, T., Constituents of the roots of Boerhaavia diffusa L. I. Examination of sterols and structures of new rotenoids, boeravinones A and B. Chem. Pharm. Bull., 37, 3214-3220 (1989) https://doi.org/10.1248/cpb.37.3214
  6. Kim, S. Y., Choi, Y. H., Huh, H., Kim, J., Kim, Y. C., and Lee, H. S., New antihepatotoxic cerebroside from Lycium chinenese fruits. J. Nat. Prod., 60, 274-276 (1997) https://doi.org/10.1021/np960670b
  7. Kitagawa, I., Hayashi, K., and Kobayashi, M., Heterosigmaglycolipids I and II, two new galactolipids containing octadecatetraenoyl and eicosapentaenoyl residues, from a raphidophyte dinoflagellate Heterosigma sp. Chem. Pharm. Bull., 37, 849-851 (1989) https://doi.org/10.1248/cpb.37.849
  8. Murakami, N., Shirahashi, H., Nagatsu, A., and Sakakibara, J., Studies on Glycolipids. VI. new acyl-distributed glyceroglycolipids from the nitrogen-fixing cyanobacterium Anabaena flos-aquae. Chem. Pharm. Bull., 41, 1177-1179 (1993) https://doi.org/10.1248/cpb.41.1177
  9. Nakano, K., Murakami, K., Nohara, T., Tomimatsu, T., and Kawasaki, T., The constituents of Paris verticillata M.v. Bieb. Chem. Pharm. Bull., 29, 1445-1451 (1981) https://doi.org/10.1248/cpb.29.1445
  10. Oshima, Y., Yamada, S.-H., Matsunaga, K., Moriya, T., and Ohizumi, Y., A monogalactosyl diacylglycerol from a cultured marine dinoflagellate, Scrippsiella trochoides. J. Nat. Prod., 57, 534-536 (1994) https://doi.org/10.1021/np50106a017