Archives of Pharmacal Research

The Pharmaceutical Society of Korea (대한약학회)
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3'-Hydroxyamentoflavone and Its 7-O-Methyl Ether, Two New Biflavonoids from Aristolochia contorta

  • Chen Ye-Gao (Department of Chemistry, Hainan Normal University) ;
  • Yu Li-Li (Department of Chemistry, Yunnan Normal University) ;
  • Huang Rang (Experimental Center, Yunnan University) ;
  • Liu Jia-Chuan (Department of Chemistry, Yunnan Normal University) ;
  • Lv Yu-Ping (Department of Chemistry, Yunnan Normal University) ;
  • Zhao Yang (Department of Chemistry, Yunnan Normal University)
  • Published : 2005.11.01
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Abstract

Two new biflavonoids, 3'-hydroxyamentoflavone-7-O-methyl ether (1) and 3'-hydroxyamentoflavone (2), were isolated from the fruits of Aristolochia contorta Bge. Their structures were elucidated by HR-ESI-MS, 1D-, and 2D-NMR spectroscopy.

Keywords

References

  1. Damu, A. G., Kuo, P. C., Leu, Y. L., Chan, Y. Y., and Wu, T. S., Chemical constituents and pharmacology of the Formosan Aristolochia species. Chin. Pharm. J., 55, 1-33 (2003)
  2. Fernando, J. C. C., Boralle, N., Silva, H. S. D., and Lopes, L. M. X., Bi- and tetraflavonoids from Aristolochia ridicula. Phytochemistry, 55, 823-832 (2000) https://doi.org/10.1016/S0031-9422(00)00293-4
  3. Ioset, J. R., Raoelison, G. E., and Hostettmann, K., Detection of aristolochic acid in Chinese phytomedicines and dietary supplements used as slimming regimens. Food Chem. Toxicol., 41, 29-36 (2003) https://doi.org/10.1016/S0278-6915(02)00219-3
  4. Jiangsu New Medical College, Dictionary of Traditional Chinese Medicine. Shanghai People's Press, Shanghai, pp. 294 (1977)
  5. Lee, H. S. and Han, D. S., A new acylated N-glycosyl lactam from Aristolochia contorta. J. Nat. Prod., 55, 1165-1169 (1992) https://doi.org/10.1021/np50087a001
  6. Lou, F. C., Ding, L. S., Wu, M. Y., and Li, L. L., Chemical constituents form Aristolochia contorta. Acta Pharm. Sin., 21, 702-705 (1986)
  7. Lu, Y. P., Chen, Y. G., and Wen, J., A new biflavone from Selaginella doederleinii. Acta Bot. Yunnan. 26, 226-228 (2004)
  8. Nascimento, I. R. and Lopes, L. M. X., Diterpene esters of aristolochic acids from Aristolochia pubescens. Phytochemistry, 63, 953-957 (2003) https://doi.org/10.1016/S0031-9422(03)00335-2
  9. Priestap, H. A., Baren, C. M., Lira, P. D. L., Coussio, J. D., and Bandoni, A. L., Volatile constituents of Aristolochia argentina. Phytochemistry, 63, 221-225 (2003) https://doi.org/10.1016/S0031-9422(02)00751-3
  10. Shi, L. S., Kuo, P. C., Tsai, Y. L., Damu, A. G., and Wu, T. S., The alkaloids and other constituents from the root and stem of Aristolochia elegans. Bioorg. Med. Chem., 12, 439- 446 (2004) https://doi.org/10.1016/j.bmc.2003.10.031
  11. Tan, H. G. and Liu, Y. Q., Chemical constituents form the roots of Aristolochia contorta. Zhongguo Zhong Yao Za Zhi, 19, 677-678 (1994)