한국수산과학회지 (Korean Journal of Fisheries and Aquatic Sciences)

  • 제38권6호
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  • Pages.372-378
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  • 2005
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  • 0374-8111(pISSN)
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  • 2287-8815(eISSN)
한국수산과학회 (The Korean Society of Fisheries and Aquatic Science)
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HPLC를 이용한 어패류 중의 테트라사이클린계 항생제 분석방법 개발

Analysis of Tetracyclines Using Righ-Perforklance Liquid Chromatography for Fishery Products

  • LEE Hee Jung (National Fisheries Research and Development Institute) ;
  • LEE Tae Seek (National Fisheries Research and Development Institute) ;
  • SON Kwang Tae (National Fisheries Research and Development Institute) ;
  • KIM Poong Ho (National Fisheries Research and Development Institute) ;
  • JO Mi Ra (National Fisheries Research and Development Institute) ;
  • PARK Mi Jung (National Fishes Products Quality Inspection Service) ;
  • Yi Young Ho (The National Assembly)
  • 발행 : 2005.12.01
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초록

An analysis method of tetracyclines far fish and shellfish products containing large amount of low molecular materials and pigments was established. The recovery of the established analysis method for four tetracycline samples was $72-100\%$ and higher than other methods reported. Especially, proposed sample treatment protocol was shown to be effective for the removal of low molecular materials and pigments that tend to interfere with accurate analysis. The detection limit of oxytetracycline (OTC) and tetracycline (TC) from the sample was 0.02 ppm, and the detection limit of chlortetracycline (CTC) and doxycycline (DC) from the sample was 0.1ppm, To examine the efficiency of the established method and identify tetracycline usage in fish farms, tetracycline group antibiotics in the flounder being cultured was monitored. The improved method can be used for fish and shellfish products effectively and all surveyed fish farms have used tetracycline all the year round. The proposed method was adopted as official method for fishery products by Korean Food and Drug Administration in 2003 and it is being used by regulatory authority as National Fishery Products Quality Inspection Service.

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참고문헌

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피인용 문헌

  1. Effects of solids retention time on the fate of tetracycline resistance in SBRs for the treatment of carcass leachate vol.181, 2016, https://doi.org/10.1016/j.jenvman.2016.06.046
  2. Alcohol Metabolizing Activity of Fermented Sea Tangle Juice vol.43, pp.1, 2010, https://doi.org/10.5657/kfas.2010.43.1.001
  3. Residues of Antibiotics in Wild and Cultured Fishes Collected from Coast of Korea vol.43, pp.1, 2010, https://doi.org/10.5657/kfas.2010.43.1.012
  4. Application of a Solid-Phase Fluorescence Immunoassay to Determine Oxytetracycline and Tetracycline Residues in Tissue of Olive Flounder (Paralichthys olivaceus) vol.68, pp.11, 2005, https://doi.org/10.1292/jvms.68.1243