The effects of Exercise and Low-Power Laser on the Changes of the behavior in the Cerebellar Injured rats by 3-Acetylpyridine

3-AP로 인한 소뇌병변 흰쥐에서 운동과 저출력 레이저가 행동변화에 미치는 영향

  • Baek, Il-Hun (Physical Therapy Major, Graduate School of Health Science, Catholic University of Pusan) ;
  • Ha, Mi-Sook (Physical Therapy Major, Graduate School of Health Science, Catholic University of Pusan) ;
  • Ahn, So-Youn (Department of Physical Therapy, Catholic University of Pusan) ;
  • Koo, Bong-Oh (Department of Physical Therapy, Catholic University of Pusan) ;
  • Rho, Min-He (Department of Physical Therapy, Catholic University of Pusan)
  • 백일훈 (부산가톨릭대학 보건과학대학원 물리치료) ;
  • 하미숙 (부산가톨릭대학 보건과학대학원 물리치료) ;
  • 안소윤 (부산가톨릭대학교 물리치료학과) ;
  • 구봉오 (부산가톨릭대학교 물리치료학과) ;
  • 노민희 (부산가톨릭대학교 물리치료학과)
  • Published : 2005.12.31

Abstract

The purposes of this study were to test the effects of the low power laser and exercise on the recovery in the cerebellar injured rats by 3-Acetylpyridine. Cerebellar injury was induced by 3-Acetylpyridine chemoablation of the inferior olive. Thirty Sprague-Dawley rats were assigned to the normal control and 3AP control and 3 experimental groups. Each experimental group was treated from 5 days after being injured for the 5 min(laser group), 10 min(exercise group) and 15min(exercise with laser) everyday during the 2 weeks. The Hindlimb splay test, Vestibular drop test, Hindlimb stride width test, Maximal Height Vertical Jump test were examined at pre-treatment on 1st day and 5th, 10th, 14th days after treatment on the cerebellar injured rats by 3AP. The results of this experiment were as follows; There were significantly increased exercise on the 3 experimental groups comparied with the 3AP control group, in the Hindlimb splay test, Vestibular drop test, Hindlimb stride width test, and Maximal Height Jump test(P<.05).

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