Korean Journal of Microbiology (미생물학회지)

The Microbiological Society of Korea (한국미생물학회)
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Effect of Light Conditions on Production of Cordycepin of Cordyceps militaris

광조건이 Codyceps militaris의 Cordycepin 생산에 미치는 영향

  • Jo Sung-Jun (Department of Biology, Graduate School, Graduate School, Dongguk University) ;
  • Lee Tae-Hee (Department of Biology, Graduate School, Graduate School, Dongguk University) ;
  • Chae Dae-Hoon (Dongseo Pharm. Co.,) ;
  • Han Yeong-Hwan (Department of Life Science, College of Natural Science, Dongguk University)
  • Published : 2005.09.01
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Abstract

The effect of light on production of cordycepin (3'-deoxyadenosine) was investigated using Cordyceps militaris. Among Cordyceps spp. tested, C. militaris KCTC 6064 was the best for cordycepin production, After 120-hr cultivation of C. militaris KCTC 6064 at $24^{\circ}C$ in YMG broth with light (1,000 lux), 51.6 mg/l of cordycepin was produced. In general, production of cordycepin with light illumination was better than that without light. Cordycepin production under light illumination was enhanced up 96-hr cultivation, whereas after 96-hr, cordycepin production was decreased.

Cordyceps militaris의 액체배양시 cordycepin(3'-deoxyadenosine) 생산성에 영향을 주는 광조건의 영향을 조사하였다. 사용된 Cordyceps 속균중에서 C. militaris KCTC 6064가 우수한 cordycepin 생산성을 보여주었다. 광조건(1,000 lux)에서 YM배지에 C.militaris KCTC 6064을 120시간 배양한 결과, 51.6 mg/l의 가장 우수한 cordycepin 생산성을 보여주었다. 광조건에서의 cordycepin 생산성은 96시간 배양까지는 증가되었으나, 96시간 이후에는 cordycepin 생산이 감소하였다.

Keywords

References

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