한국수산과학회지 (Korean Journal of Fisheries and Aquatic Sciences)

  • 제38권4호
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  • Pages.219-225
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  • 2005
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  • 0374-8111(pISSN)
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  • 2287-8815(eISSN)
한국수산과학회 (The Korean Society of Fisheries and Aquatic Science)
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가다랑어 훈연조미제품 유래 저분자물질의 생리활성

Biological Activities of Low Molecular Weight Substances Fractionated from the Seasoned and Smoked Products of Skipjack Tuna (Euthynus pelamis)

  • 이정민 (강릉대학교 행양생명공학부) ;
  • 최근표 (강원전문대학 식품생명과학과) ;
  • 원무호 (한림대학교 의과대학) ;
  • 김상무 (강릉대학교 해양생명공학부)
  • LEE Jung Min (Faculty of Marine Bioscience and Technology, Kangnung National University) ;
  • CHOI Geun Pyo (Department of Food and Life Science, Gangwon Provincial University) ;
  • WON Moo Ho (College of Medicine, Hallym University) ;
  • KIM Sang Moo (Faculty of Marine Bioscience and Technology, Kangnung National University)
  • 발행 : 2005.08.01
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초록

We studied the anticancer, antioxidative, ACE inhibitory, antithrombic, and cerebral ischemia inhibitory activities, of low molecular weight substances fractionated from the seasoned and smoked products of skipjack tuna (Euthynus pelamis). Low molecular weight substances fractionated from the liquid extract of seasoned and smoked skipjack tuna powder showed 7 peaks on gel permeation chromatography. Anticancer activity was the highest at Peak 3 $(54.23%)$ followed by Peak 4 $(41.58\%)$. The potency order of antioxidative activity was the highest at Peak 3 $(94.14\%)$ followed by Peak 2 $(82.07\%)$ and Peak 5 $(81.24\%)$. ACE inhibitory activity was the highest at Peak 3 $(67.27\%)$ followed by Peak 5 $(45.62\%)$. But there was weak anti thrombotic effect (PT and APTT) in the low molecular weight substances of the seasoned and smoked products of skipjack tuna. Cerebral ischemia inhibitory activity was the highest at Peak 3 $(80.0\%)$ followed by Peak 5 $(40.0\%)$.

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