Journal of Physiology & Pathology in Korean Medicine (동의생리병리학회지)

The Physiological Society of Korean Medicine and The Society of Pathology in Korean Medicine (대한동의생리학회·한의병리학회)
권호 표지

In Vivo Studies on Anti-inflammatory Activity of Nephrite

급성염증 동물모델에서 연옥분과 연옥수의 염증억제 효과

  • Han Dong-Oh (Department of Acupuncture & Meridian, Graduate School of East-West Medical Science, Kyung-Hee University) ;
  • Choi Bo-Hee (Bokyung Nephrite Co.,) ;
  • Lee Hye-Jung (Department of Acupuncture & Meridian, Graduate School of East-West Medical Science, Kyung-Hee University) ;
  • Shim Insop (Department of Integrative Medicine, College of Medicine, The Catholic University of Korea) ;
  • Kang Sung-Keel (Department of Acupuncture & Moxibustion, College of Oriental Medicine, Kyung-Hee University) ;
  • Hahm Dae-Hyun (Department of Acupuncture & Meridian, Graduate School of East-West Medical Science, Kyung-Hee University)
  • 한동오 (경희대학교 동서의학대학원 침구경락학교실) ;
  • 최보희 (㈜보경연옥) ;
  • 이혜정 (경희대학교 동서의학대학원 침구경락학교실) ;
  • 심인섭 (가톨릭의과대학 통합의학과) ;
  • 강성길 (경희대학교 경희의료원 한방병원 침구과) ;
  • 함대현 (경희대학교 동서의학대학원 침구경락학교실)
  • Published : 2005.08.01
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Abstract

Most inflammatory disorders are usually treated using anti-inflammatory drugs including non-steroidal anti-inflammatory drugs (NSAID) and steroidal anti-inflammatory drugs (SAID). In a prolonged use, however, they may frequently produce adverse side-effects. Thus, it is necessarily required to develop a new anti-inflammatory drug with little side-effects. Nephrite has been widely used by traditional oriental medicine to cure the various chronic diseases. In order to verify the anti-inflammatory activity of nephrite, the TPA (12-O-tetradecanoylphorbol-acetate) or the croton oil-induced edema was developed in the mouse ears and the nephrite powder suspension or the nephrite water was directly applied to the ear edema. It was found that nephrite could significantly reduce the ear swelling implying its strong potential as an active anti-inflammatory agent when comparing to indomethacin, a non-steroidal anti-inflammatory drug.

Keywords

References

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