Archives of Pharmacal Research

The Pharmaceutical Society of Korea (대한약학회)
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Antibacterial Constituents from Fruit Bodies of Ascomyce Bulgaria inquinans

  • Zhang Peng (Research Department of Natural Medicine, Shenyang Pharmaceutical University) ;
  • Li Xian (Research Department of Natural Medicine, Shenyang Pharmaceutical University) ;
  • Li Ning (Research Department of Natural Medicine, Shenyang Pharmaceutical University) ;
  • Xu Jing (Research Department of Natural Medicine, Shenyang Pharmaceutical University) ;
  • Li Zhan-Lin (Research Department of Natural Medicine, Shenyang Pharmaceutical University) ;
  • Wang Yi (Research Department of Natural Medicine, Shenyang Pharmaceutical University) ;
  • Wang Jin-Hui (Research Department of Natural Medicine, Shenyang Pharmaceutical University)
  • Published : 2005.08.01
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Abstract

Two ergosterins and two triterpenoids were isolated from the dried fruit bodies of Ascomyce Bulgaria inquinans. By means of chemical (hydrolysis) and spectroscopic methods (NMR, EIMS), their structures were established as betuinic acid (1), cerevisterol (2), (24R)ergosta-7, $22E­diene-3\beta,\;5\alpha,\;6\beta-triol-3-O-palmitate$ (3) and ursolic acid (4). Compound 3 is a new compound.

Keywords

References

  1. Dale, G. N., McClatchey, W. C., and Gerwick, W. H., New glycosphingolipids from the marine sponge Halichondria pannicea. J. Nat. Prod., 55, 1013-1017 (1992) https://doi.org/10.1021/np50085a032
  2. Junichi Kitajima, Masami Shindo, and Yasuko Tanaka, Oleanderol, a new pentacyclic triterpene from the leaves of nerium oleander. Chem. Pharm. Bull., 38, 714-716 (1990) https://doi.org/10.1248/cpb.38.714
  3. Mahoto, S. B. and Kundu, A. P., $^{13}C$-NMR Spectra of Pentacyclic triterpenoids-a compilation and some salient features. Phytochemistry, 37, 1517-1575 (1994) https://doi.org/10.1016/S0031-9422(00)89569-2
  4. Stadler, M., Anke, H., Dekermendjlan, K., Reiss, R., Sterner, O., and Witt, R., Novel Bioactive azaphilones from fruit bodies and mycelial cultures of the Ascomycete Bulgaria inquinans (Fr.). Natural Product Letters, 7, 7-14 (1995) https://doi.org/10.1080/10575639508043180
  5. Raymond, L. Edwards and Howard, J. Lockett, Constituents of the Higher Fungi. Part XVI. Bulgarhodin and bulgarein. novel benzofluoranthenequinones from the fungus Bugaria inquinans. J. Chem. Soc. Perkin I, 2419 (1976)
  6. Sun, Hong-xiang, Ye, Yi-ping, and Yang, Ke, Studies on the chemical constituents in Radix Astilkes Chinensis. China. Journal of Chinese Materia Medica, 27, 751-754 (2002)
  7. Yoshihisa Takaishi, Minoru Uda, Takashi Ohashi, Kimiko Nakano, Koutarou Murakami, and Toshiaki Tomimatsu, Glycosides of ergosterol derivatives from Hericum erinacens. Phytochemistry, 30, 4117-4120 (1991) https://doi.org/10.1016/0031-9422(91)83478-4