Natural Product Sciences

The Korean Society of Pharmacognosy (한국생약학회)
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Trisoxazole Macrolide from a Marine Sponge Sarcotragus Species

  • Liu, Yong-Hong (College of Pharmacy, Pusan National University) ;
  • Shinde, Pramod B. (College of Pharmacy, Pusan National University) ;
  • Hong, Jong-Ki (Hazardous Substance Research Team, Korea Basic Science Institute) ;
  • Lee, Chong-O. (Pharmaceutical Screening Center, Korea Research Institute of Chemical Technology) ;
  • Im, Kwang-Sik (College of Pharmacy, Pusan National University) ;
  • Jung, Jee-H. (College of Pharmacy, Pusan National University)
  • Published : 2005.03.01
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Abstract

Bioassay-directed fractionation of the lipophilic extract of a marine sponge Sarcotragus sp. led to the isolation of a known trisoxazole containing macrolide, mycalolide B (1). Its structure was identified by NMR and MS analyses. This is the first report on the isolation of macrolide from a sponge of the genus Sarcotragus (Order: Dictyoceratida).

Keywords

References

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