The Journal of Pediatrics of Korean Medicine (대한한방소아과학회지)

The Association of Korean Oriental Pediatrics (대한한방소아과학회)
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The Effects of Kamiyangsintang(KYT) to Cold-Stress

가미양신탕(加味養神湯)이 저온(低溫) 스트레스에 미치는 영향

  • Han, Jae-Kyung (Department of Pediatrics, College of Oriental Medicine, Dae-jeon University) ;
  • Kim, Yun-Hee (Department of Pediatrics, College of Oriental Medicine, Dae-jeon University) ;
  • Jung, Chang-Ho (Department of Pediatrics, College of Oriental Medicine, Dae-jeon University)
  • 한재경 (대전대학교 한의과대학 소아과학교실) ;
  • 김윤희 (대전대학교 한의과대학 소아과학교실) ;
  • 정창호 (대전대학교 한의과대학 소아과학교실)
  • Published : 2005.12.31
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Abstract

Objective : The study was aimed to evaluate the anti-stress effect of KYT on the cold-stressed Mice. Methods: The experimental animals were stressed in cold room $(4{\pm}0.5^{\circ}C)$ for one hour in a day during two weeks, and administred 131mg/100g KYT extract for two weeks before stress. For two weeks, while the experiment was taking place, we conducted a research about the change of weight and content of norepinephrine, epinephrine, dopamine, cortisol and GOT, GPT in the mice serum. Results : KYT extract significantly inhibited the decrease of body weight induced by stress, compared with the control group. KYT extract had no significant decreasing effect on the change of content of the serum GOT but had significant decreasing effect on the change of content of the serum GPT compared with the control group. KYT extract had significant decreasing effect on the change of content of the serum cortisol compared with the control group. KYT extract had decreasing effect on the change of content of the serum dopamine compared with the control group. KYT extract had no decreasing effect on the change of content of the serum norepinephrine compared with the control group. KYT extract had significant decreasing effect on the change of content of the serum epinephrine compared with the control group. Conclusions : According to the above results, it is concluded that KYT will be useful as a preventive and remedy against stress disease.

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