The Journal of Internal Korean Medicine (대한한방내과학회지)
- Volume 26 Issue 3
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- Pages.551-562
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- 2005
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- 1226-9174(pISSN)
The Effects of Trichosanthis Semen Herbal-acupuncture in ovalbumin-induced asthma mouse model
과루인약침(瓜蔞仁藥鍼)이 Ovalbumin-induced Asthma Mouse Model에 미치는 영향(影響)
- Kim, Jung-Hyun (Department of Internal Medicine, College of Oriental Medicine, Daejeon University) ;
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Baek, Kyung-Min
(Department of Internal Medicine, College of Oriental Medicine, Daejeon University) ;
- Lee, Hyun-Eui (Department of Internal Medicine, College of Oriental Medicine, Daejeon University) ;
- Kim, Jong-Won (Department of Internal Medicine, College of Oriental Medicine, Daejeon University) ;
- Oh, Byeong-Yeol (Department of Internal Medicine, College of Oriental Medicine, Daejeon University) ;
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Jo, Hyun-Kyung
(Department of Internal Medicine, College of Oriental Medicine, Daejeon University) ;
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Yoo, Ho-Rhyong
(Department of Internal Medicine, College of Oriental Medicine, Daejeon University) ;
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Kim, Yoon-Sik
(Department of Internal Medicine, College of Oriental Medicine, Daejeon University) ;
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Seol, In-Chan
(Department of Internal Medicine, College of Oriental Medicine, Daejeon University) ;
- Shim, Jae-Chul (Department of Internal Medicine, College of Oriental Medicine, Daejeon University)
- 김정현 (대전대학교부속한방병원 내과학교실) ;
-
백경민
(대전대학교부속한방병원 내과학교실) ;
- 이현의 (대전대학교부속한방병원 내과학교실) ;
- 김종원 (대전대학교부속한방병원 내과학교실) ;
- 오병열 (대전대학교부속한방병원 내과학교실) ;
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조현경
(대전대학교부속한방병원 내과학교실) ;
-
유호룡
(대전대학교부속한방병원 내과학교실) ;
-
김윤식
(대전대학교부속한방병원 내과학교실) ;
-
설인찬
(대전대학교부속한방병원 내과학교실) ;
- 심재철 (대전대학교부속한방병원 내과학교실)
- Published : 2005.09.30
Abstract
Objectives : The aim of this study was to investigate the effect of Trichosanthis Semen Herbal-acupuncture(TS-HA) at Joksamni(ST36) on ovalbumin-induced asthma in mice. Methods : C57BL/6 mice were sensitized and challenged with ovalbumin(OVA) once a week for twelve weeks. The experimental group was treated with 1% concentrations of TS-HA at Joksamni(ST36) three times a week for the last eight weeks. Results : 1. The weight and total lung cells of the mice in the group treated with TS-HA decreased significantly compared with those of control group. 2. Total leukocytes and eosinophils in Bronchoalveoler-lavage fluid(BALF) of the mice in the group treated with TS-HA decreased significantly compared with those of control group. 3. Eosinophils in BALF of the mice in the group treated with TS-HA in photomicrographs decreased significantly compared with those of control group. 4. According to histological analysis of lung sections, adhension of collagen in TS-HA decreased significantly compared with that of control group. 5. The concentration of IgE, IL-4, IL-5 in BALF and IL-4, IL-5, IL-13 in serum of the mice in the group treated with TS-HA decreased significantly compared with that of control group. 6. The number of