Journal of Physiology & Pathology in Korean Medicine (동의생리병리학회지)

The Physiological Society of Korean Medicine and The Society of Pathology in Korean Medicine (대한동의생리학회·한의병리학회)
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Antifungal Activity of Chloroform Extract from Riccardia marginata on the Dermatophytic Fungus Trichophyton mentagrophytes

  • Na, Young-Soon (Department of Beauty, Konyang University) ;
  • Lee, Hong (Division of Bionano Chemistry, Wonkwang University) ;
  • Kim, Myung-Ju (Department of Skin & Beauty, Kwangju Health Science College) ;
  • Oh, Hyun-Ju (Department of Beauty Art, Honam University) ;
  • Baek, Seung-Hwa (Department of Herbal Resources, Professional Graduate School of Oriental Medicine and Institute of Basic Natural Sciences, Wonkwang University)
  • Published : 2005.04.25
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Abstract

The effects of chloroform extract from Riccardia marginata on antifungal activity were investigated. The crude chloroform extract of R. marginata inhibited the growth of the Gram positive bacterium Bacillus subtilis ATCC 19659, (4 mm inhibition zone at $150\;{\mu}g/disc$) and the dermatophytic fungus Trichophyton mentagrophytes ATCC 28185, (6 mm inhibition zone at $150\;{\mu}g/disc$), and inactive to P388 murine leukaemia cells ATCC CCL 46 P388D1, ($IC_{50}\;>25,000\;{\mu}g/mL$ at $150\;{\mu}g/disc$). This crude chloroform extract of R. marginata showed strong antifungal activity against the dermatophytic fungus Trichophyton mentagrophytes.

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References

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