Antifungal Activity of the Crude Extract from Quintinia acutifolia on the Dermatophytic fungus

  • Lee, Jae-Sook (Department of Hair Design, Gongju Communication Art College) ;
  • Chung, Jong-Gab (Department of Food and Nutrition, Wonkwang Health Science College) ;
  • Oh, Hyun-Ju (Department of Beauty Art, Honam University) ;
  • Na, Young-Soon (Department of Beauty, Konyang University) ;
  • Baek, Seung-Hwa (Department of Herbal Resources, Professional Graduate School of Oriental Medicine and Institute of Basic Natural Sciences, Wonkwang University)
  • Published : 2005.04.25

Abstract

The crude extract of Quintinia acutifolia Kirk inhibited the growth of the Gram positive bacterium Bacillus subtilis ATCC 19659, (3 mm inhibition zone at $150\;{\mu}g/disc$) and the dermatophytic fungus Trichophyton mentagrophytes ATCC 28185, (3 mm inhibition zone at $150\;{\mu}g/disc$), and cytotoxic to P388 murine leukaemia cells ATCC CCL 46 P388D1, ($IC_{50}$ $50,000\;{\mu}g/mL$ at $150\;{\mu}g/disc$). However, Candida albicans (ATCC 14053) did not observed the antimicrobial activity and the cytotoxic activity to BSC monkey kidney cells ($({\alpha})$ 5 mg/mL, $150\;{\mu}g/disc$).

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References

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