Journal of Physiology & Pathology in Korean Medicine (동의생리병리학회지)

The Physiological Society of Korean Medicine and The Society of Pathology in Korean Medicine (대한동의생리학회·한의병리학회)
권호 표지

Effect of Germinated Seed of Rhynchosia Volubilis on Cathepsin-K in Ovariectomized Rats

발아(發芽)한 서목태(鼠目太)가 난소적출 흰쥐의 Cathepsin-K에 미치는 영향

  • Jung, Ho-Long (Department of Oriental Rehabilitaion Medicine, College of Oriental Medicine, Sang-ji University) ;
  • Lee, Eung-Se (Department of Oriental Rehabilitaion Medicine, College of Oriental Medicine, Sang-ji University) ;
  • Cha, Yun-Yeop (Department of Oriental Rehabilitaion Medicine, College of Oriental Medicine, Sang-ji University)
  • 정호롱 (상지대학교 한의과대학 한방재활의학과교실) ;
  • 이응세 (상지대학교 한의과대학 한방재활의학과교실) ;
  • 차윤엽 (상지대학교 한의과대학 한방재활의학과교실)
  • Published : 2005.02.25
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Abstract

The aim of this study is to find out what inhibition effects the Germinated Seed of Rhynchosia Volubilis(GSRV) has by its feeding period on the bone absorption in ovariectomized white rats. Close examination of the amounts of the Cathepsin-K in the rats by the groups of one, two and three-day germination periods led to the following conclusions. Feeding non-ovariectomized white rats with GSRV by the groups of one, two and three-day germination periods showed less amounts of Cathepsin-K in their proximal tibia in all the feeding periods of two, three and four weeks than in the case of control group, revealing a statistical significance. Feeding ovariectomized white rats with GSRV by the groups of one, two and three-day germination periods showed less amounts of Cathepsin-K in their proximal tibia in all the feeding periods of two, three and four weeks than in the case of the control group, revealing a statistical significance. Therefore, the Germinated Seed of Rhynchosia Volubilis(GSRV) is believed to have inhibition effects on bone resorption.

Keywords

References

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