A Study on the Durability and Synthesis of Sulfa Agents Using Glutaraldehyde

Glutaraldehyde를 이용한 설파제의 합성과 지속성에 관한 연구

  • Yoon Cheol Hun (Department of Chemical Engineering, DaeJin University)
  • 윤철훈 (대진대학교 화학공학과)
  • Published : 2004.12.01

Abstract

Dual actions are the most recently used delivery system in drug study. Dual-action agents are unique chemical entities comprised of two different type of antibacterial compounds covalently linked together in a single molecule in such a way that both components are able to exert their bactericidal properties. Crosslinked sulfadiazine-sulfanilamide such as antibiotics is synthesized by synthetic handle with glutaraldehyde. As a result, New synthetic antibacterial agent exhibited the broad antibacterial activities against Gram(+) and Gram(-) of 4 strains and a long durability supposing that the stomach and blood.

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