Massive Pleural Effusion as the First Manifestation of Malignant Melanoma Metastasis

흉수로 발현한 전이성 악성 흑색종 1예

  • Kim, Hee Gu (Department of Internal Medicine, Inha University College of Medicine) ;
  • Ryu, Jeong Seon (Department of Internal Medicine, Inha University College of Medicine) ;
  • Kwak, Seung Min (Department of Internal Medicine, Inha University College of Medicine) ;
  • Lee, Hong Lyeol (Department of Internal Medicine, Inha University College of Medicine) ;
  • Kim, Lucia (Department of Pathology, Inha University College of Medicine) ;
  • Cho, Jae Hwa (Department of Internal Medicine, Inha University College of Medicine)
  • 김희구 (인하대학교 의과대학 내과학교실) ;
  • 류정선 (인하대학교 의과대학 내과학교실) ;
  • 곽승민 (인하대학교 의과대학 내과학교실) ;
  • 이홍렬 (인하대학교 의과대학 내과학교실) ;
  • 김루시아 (인하대학교 의과대학 해부병리학교실) ;
  • 조재화 (인하대학교 의과대학 내과학교실)
  • Received : 2004.05.10
  • Accepted : 2004.07.23
  • Published : 2004.09.30

Abstract

Malignant melanoma develops from melanocytes and frequently metastases to other organs. Common metastatic sites are other skin, lymph nodes, lung, liver, brain and bone in decreasing order of frequency. Malignant pleural effusion is less frequent manifestation of thoracic metastasis. We experienced a 57-year-old man with pleural effusion who received radical resection with local flap on left foot due to acral lentiginous melanoma 3 years ago. He had progressive chest pain and left massive pleural effusion. The pleural cytology and biopsy showed malignant melanoma. After closed thoracostomy and talc pleurodesis, he refused further immunotherapy and chemotherapy and discharged.

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