Tuberculosis and Respiratory Diseases

The Korean Academy of Tuberculosis and Respiratory Diseases (대한결핵및호흡기학회)
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A Case of Central Diabetes Insipidus in Patient with Non-small Cell Lung Cancer

비소세포폐암에 합병된 중추성 요붕증 1예

  • Hwang, Eun Mi (Division of Pulmonology, Department of Internal Medicine, The Catholic University of Korea, College of Medicine) ;
  • Oh, You Kyoung (Division of Pulmonology, Department of Internal Medicine, The Catholic University of Korea, College of Medicine) ;
  • Kim, Ki Jo (Division of Pulmonology, Department of Internal Medicine, The Catholic University of Korea, College of Medicine) ;
  • Kim, Yong Hyun (Division of Pulmonology, Department of Internal Medicine, The Catholic University of Korea, College of Medicine) ;
  • Yoon, Hyoung Kyu (Division of Pulmonology, Department of Internal Medicine, The Catholic University of Korea, College of Medicine) ;
  • Song, Jeong Sup (Division of Pulmonology, Department of Internal Medicine, The Catholic University of Korea, College of Medicine)
  • 황은미 (가톨릭대학교 의과대학 내과학교실) ;
  • 오유경 (가톨릭대학교 의과대학 내과학교실) ;
  • 김기조 (가톨릭대학교 의과대학 내과학교실) ;
  • 김용현 (가톨릭대학교 의과대학 내과학교실) ;
  • 윤형규 (가톨릭대학교 의과대학 내과학교실) ;
  • 송정섭 (가톨릭대학교 의과대학 내과학교실)
  • Received : 2004.01.29
  • Accepted : 2004.07.19
  • Published : 2004.09.30
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Abstract

Central diabetes insipidus (DI) is a disease caused by insufficient release of antidiuretic hormone. Central DI with lung cancer is very rare. Most of them are caused by the pituitary metastasis, and rarely, by the paraneoplastic syndromes. Central DI is diagnosed by the water deprivation test. The treatment consists of surgical resection, radiotherapy and administration of desmopressin. We report an unusual case of central DI with non-small cell lung cancer. The diagnosis was confirmed by water deprivation test. After the administration of desmopressin, the urine osmolarity was increased. The patient's symptoms and urine osmolarity were improved by intranasal desmopressin.

폐암에서 중추성 요붕증이 병합되는 경우는 드물며, 그 원인은 대개 뇌하수체로의 전이에 의한 것으로, 이런 경우 수술적 치료나 방사선 치료가 도움이 된다. 그러나 부종양성 증후군의 일부로 발현될 수도 있으며, 이 경우에는 데스모프레신으로 효과적으로 치료할 수 있다. 저자들은 갈증, 다음, 다뇨를 주소로 내원한 비소세포폐암 환자에서 수분제한검사로 중추성 요붕증을 확진한 환자를 경험하였기에 이를 보고하는 바이다.

Keywords

References

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